Maternal Anti-Dengue IgG Fucosylation Predicts Susceptibility to Dengue Disease in Infants

Infant mortality from dengue disease is a devastating global health burden that could be minimized with the ability to identify susceptibility for severe disease prior to infection. Although most primary infant dengue infections are asymptomatic, maternally derived anti-dengue immunoglobulin G (IgGs...

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Veröffentlicht in:	Cell reports (Cambridge) 2020-05, Vol.31 (6), p.107642-107642, Article 107642
Hauptverfasser:	Thulin, Natalie K., Brewer, R. Camille, Sherwood, Robert, Bournazos, Stylianos, Edwards, Karlie G., Ramadoss, Nitya S., Taubenberger, Jeffery K., Memoli, Matthew, Gentles, Andrew J., Jagannathan, Prasanna, Zhang, Sheng, Libraty, Daniel H., Wang, Taia T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Anti-Idiotypic - genetics antibody glycosylation CD16 Dengue Virus - genetics FcγRIIIa Female Humans IgG fucosylation Infant infant dengue Infant, Newborn severe dengue Severe Dengue - virology
Online-Zugang:	Volltext
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