Prognostic value of MYD88 L265P mutation in diffuse large B cell lymphoma via droplet digital PCR

To assess the prevalence and prognostic value of myeloid differentiation factor 88 (MYD88) expression and mutational status in diffuse large B cell lymphoma (DLBCL), a total cohort of 100 patients with DLBCL were studied using immunohistochemistry (IHC) and droplet digital polymerase chain reaction ...

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Veröffentlicht in:	Molecular medicine reports 2020-08, Vol.22 (2), p.1243-1256
Hauptverfasser:	Niu, Jing, Ma, Zhiping, Nuerlan, Aijiang, Li, Sijing, Cui, Wenli, Gao, Haixia, Abulajiang, Gulinaer, Zhang, Wei, Li, Xinxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Cell differentiation Central Nervous System Neoplasms - diagnosis Central Nervous System Neoplasms - genetics Central Nervous System Neoplasms - pathology Correlation of Data Female Follow-Up Studies Gene mutations Genetic aspects Humans Immunohistochemistry Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - pathology Male Medical research Medicine, Experimental Microfluidic Analytical Techniques - methods Middle Aged Mutation Rate Myeloid Differentiation Factor 88 - genetics Myeloid Differentiation Factor 88 - metabolism Non-Hodgkin's lymphomas Polymerase Chain Reaction - methods Prognosis Survival Analysis Vincristine
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