Translation at first sight: the influence of leading codons

Abstract First triplets of mRNA coding region affect the yield of translation. We have applied the flowseq method to analyze >30 000 variants of the codons 2–11 of the fluorescent protein reporter to identify factors affecting the protein synthesis. While the negative influence of mRNA secondary...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2020-07, Vol.48 (12), p.6931-6942
Hauptverfasser:	Osterman, Ilya A, Chervontseva, Zoe S, Evfratov, Sergey A, Sorokina, Alena V, Rodin, Vladimir A, Rubtsova, Maria P, Komarova, Ekaterina S, Zatsepin, Timofei S, Kabilov, Marsel R, Bogdanov, Alexey A, Gelfand, Mikhail S, Dontsova, Olga A, Sergiev, Petr V
Format:	Artikel
Sprache:	eng
Schlagworte:	RNA and RNA-protein complexes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!