Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sjögren's syndrome reveals a pathogenic signature

In primary Sjögren's syndrome (pSS), FcRL4+ B cells are present in inflamed salivary gland tissue, within or in close proximity to ductal epithelium. FcRL4 is also expressed by nearly all pSS-related mucosa-associated lymphoid tissue (MALT) B cell lymphomas, linking FcRL4 expression to lymphoma...

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Veröffentlicht in:	Journal of autoimmunity 2020-05, Vol.109, p.102439-102439, Article 102439
Hauptverfasser:	Verstappen, Gwenny M., Ice, John A., Bootsma, Hendrika, Pringle, Sarah, Haacke, Erlin A., de Lange, Kim, van der Vries, Gerben B., Hickey, Peter, Vissink, Arjan, Spijkervet, Frederik K.L., Lessard, Christopher J., Kroese, Frans G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmunity B lymphocytes Epithelium MALT lymphoma RNA sequencing Salivary gland Sjögren's syndrome
Online-Zugang:	Volltext
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