Bioinformatics analysis of the network of histone H3 lysine 9 trimethylation in acute myeloid leukaemia

Changes in histone H3 lysine 9 trimethylation (H3K9me3) may be related to the development of drug‑resistant acute myeloid leukaemia (AML); insights into the network of H3K9me3 may improve patient prognosis. Patient data were derived from the Gene Expression Omnibus (GEO) database and data from AML c...

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Veröffentlicht in:	Oncology reports 2020-08, Vol.44 (2), p.543-554
Hauptverfasser:	Dong, Aishu, Yang, Wenbin, Huang, He, Zhou, Xiaohai, He, Zhewei, Yao, Rongxing, Guo, Wenjian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminopyridines - therapeutic use Apoptosis Benzamides - therapeutic use Chromatin Immunoprecipitation Sequencing Computational Biology - methods Drug Resistance, Neoplasm Gene expression Gene Regulatory Networks Genes Genetic aspects Histone Deacetylase Inhibitors - therapeutic use Histones - metabolism Humans Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - genetics Lysine Medical research Protein Interaction Maps THP-1 Cells
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