Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder

Background Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors. Epigenetic alterations in the oxytocin receptor gene (OXTR) may be a molecular mechanism in the pathogenesis of obsessive-compulsive diso...

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Veröffentlicht in:	Clinical epigenetics 2020-07, Vol.12 (1), p.1-101, Article 101
Hauptverfasser:	Park, Chun Il, Kim, Hae Won, Jeon, Sumoa, Kang, Jee In, Kim, Se Joo
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Analysis Cognition CpG islands Cytosine Deoxyribonucleic acid DNA DNA methylation Epigenetic inheritance Epigenetics Genes Genetic aspects Genetic research Guanine Medical research Methylation Neuromodulation Obsessive compulsive disorder Oxytocin Oxytocin receptors Phosphates Pyrimidines Studies
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