EBV renders B cells susceptible to HIV-1 in humanized mice

HIV and EBV are human pathogens that cause a considerable burden to worldwide health. In combination, these viruses are linked to AIDS-associated lymphomas. We found that EBV, which transforms B cells, renders them susceptible to HIV-1 infection in a CXCR4 and CD4-dependent manner in vitro and that...

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Veröffentlicht in:	Life science alliance 2020-08, Vol.3 (8), p.e202000640
Hauptverfasser:	McHugh, Donal, Myburgh, Renier, Caduff, Nicole, Spohn, Michael, Kok, Yik Lim, Keller, Christian W, Murer, Anita, Chatterjee, Bithi, Rühl, Julia, Engelmann, Christine, Chijioke, Obinna, Quast, Isaak, Shilaih, Mohaned, Strouvelle, Victoria P, Neumann, Kathrin, Menter, Thomas, Dirnhofer, Stephan, Lam, Janice KP, Hui, Kwai F, Bredl, Simon, Schlaepfer, Erika, Sorce, Silvia, Zbinden, Andrea, Capaul, Riccarda, Lünemann, Jan D, Aguzzi, Adriano, Chiang, Alan KS, Kempf, Werner, Trkola, Alexandra, Metzner, Karin J, Manz, Markus G, Grundhoff, Adam, Speck, Roberto F, Münz, Christian
Format:	Artikel
Sprache:	eng
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