Polygonum multiflorum Thunb. Extract Stimulates Melanogenesis by Induction of COX2 Expression through the Activation of p38 MAPK in B16F10 Mouse Melanoma Cells

Polygonum multiflorum Thunb. (PM) root extracts have been used for treating graying hair in Oriental medicine; however, the molecular mechanisms underlying the melanogenic effects of PM root have not been fully understood. In the present study, we investigated the melanogenic effects of an ethanolic...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-10
Hauptverfasser:	Kim, Donghee, Jun, Hee-Sook, Kim, Hyo-Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Cell viability Cyclooxygenase-2 Cytotoxicity Enzymes Genetic transcription Hair Kinases MAP kinase Melanin Melanoma Microphthalmia-associated transcription factor Mitogens Molecular modelling Polygonum multiflorum Protein kinase Protein kinases Proteins Vitiligo
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