Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1

Chondroitin polymerizing factor (CHPF) is an important member of glycosyltransferases involved in the biosynthesis of chondroitin sulfate (CS). However, the relationship between CHPF and malignant melanoma (MM) is still unknown. In this study, it was demonstrated that CHPF was up-regulated in MM tis...

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Veröffentlicht in:	Cell death & disease 2020-07, Vol.11 (7), p.496, Article 496
Hauptverfasser:	Sun, Wei, Zhao, Fang, Xu, Yu, Huang, Kai, Guo, Xianling, Zheng, Biqiang, Liu, Xin, Luo, Zhiguo, Kong, Yunyi, Xu, Midie, Schadendorf, Dirk, Chen, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/2 13/51 38/22 38/77 38/91 45/77 631/45/881 631/67/1813 Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Carcinogenesis - metabolism Carcinogenesis - pathology CDC2 Protein Kinase - metabolism Cell Biology Cell Culture Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Chondroitin sulfate Disease Progression Epithelial-Mesenchymal Transition Female Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Immunology Life Sciences Male Melanoma Melanoma - enzymology Melanoma - genetics Melanoma - metabolism Melanoma - pathology Middle Aged N-Acetylgalactosaminyltransferases Overexpression Ribonucleic acid RNA Skin - metabolism Skin - pathology Skin cancer Tumorigenicity
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