Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA
Abstract Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to invest...
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| Veröffentlicht in: | Medical mycology (Oxford) 2020-07, Vol.58 (5), p.609-616 |
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| creator | Shelnutt, Leslie M Kaneene, John B Carneiro, Paulo A M Langlois, Daniel K |
| description | Abstract
Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to investigate the prevalence and distribution of canine blastomycosis cases in Michigan and to identify risk factors for infection. Over 200 primary care veterinary clinics throughout the state were surveyed regarding blastomycosis prevalence, and demographic information was obtained from medical records of affected dogs that were evaluated at these clinics. A retrospective case control study was conducted for an additional 49 dogs with blastomycosis that were evaluated at specialty referral centers located in the southern mid-Michigan region. Prevalence rates were calculated for each county, and cases were mapped using geocoding software. Univariable and multivariable analyses were used to identify risk factors for infection. Prevalence rates were ≥100 cases per 100,000 dogs in five counties. Most blastomycosis cases originated from the Upper Peninsula or from a high-density area in the northern Lower Peninsula. Multivariable regression analysis identified travel or residence north of the 45th parallel as a strong risk factor for infection (P |
| doi_str_mv | 10.1093/mmy/myz110 |
| format | Article |
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Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to investigate the prevalence and distribution of canine blastomycosis cases in Michigan and to identify risk factors for infection. Over 200 primary care veterinary clinics throughout the state were surveyed regarding blastomycosis prevalence, and demographic information was obtained from medical records of affected dogs that were evaluated at these clinics. A retrospective case control study was conducted for an additional 49 dogs with blastomycosis that were evaluated at specialty referral centers located in the southern mid-Michigan region. Prevalence rates were calculated for each county, and cases were mapped using geocoding software. Univariable and multivariable analyses were used to identify risk factors for infection. Prevalence rates were ≥100 cases per 100,000 dogs in five counties. Most blastomycosis cases originated from the Upper Peninsula or from a high-density area in the northern Lower Peninsula. Multivariable regression analysis identified travel or residence north of the 45th parallel as a strong risk factor for infection (P < .001). Blastomycosis was uncommon in southern counties. These results refute previous speculations and should be of value to both human and animal health. Given that many heightened risk areas are popular tourist destinations, practitioners across the USA should be mindful of the spatial distribution of blastomycosis in Michigan.</description><identifier>ISSN: 1369-3786</identifier><identifier>EISSN: 1460-2709</identifier><identifier>DOI: 10.1093/mmy/myz110</identifier><identifier>PMID: 31732747</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Animals ; Blastomyces ; Blastomycosis - diagnosis ; Blastomycosis - epidemiology ; Blastomycosis - veterinary ; Dog Diseases - epidemiology ; Dog Diseases - microbiology ; Dogs ; Female ; Male ; Michigan - epidemiology ; Original ; Prevalence ; Retrospective Studies ; Risk Factors ; Seasons ; Surveys and Questionnaires</subject><ispartof>Medical mycology (Oxford), 2020-07, Vol.58 (5), p.609-616</ispartof><rights>The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. 2019</rights><rights>The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-fbe6bdbe5798e3221414a109c0eae1eca338ccfb79f06784a63160b3d980ffaa3</citedby><cites>FETCH-LOGICAL-c408t-fbe6bdbe5798e3221414a109c0eae1eca338ccfb79f06784a63160b3d980ffaa3</cites><orcidid>0000-0001-7726-6307</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,1578,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31732747$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shelnutt, Leslie M</creatorcontrib><creatorcontrib>Kaneene, John B</creatorcontrib><creatorcontrib>Carneiro, Paulo A M</creatorcontrib><creatorcontrib>Langlois, Daniel K</creatorcontrib><title>Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA</title><title>Medical mycology (Oxford)</title><addtitle>Med Mycol</addtitle><description>Abstract
Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to investigate the prevalence and distribution of canine blastomycosis cases in Michigan and to identify risk factors for infection. Over 200 primary care veterinary clinics throughout the state were surveyed regarding blastomycosis prevalence, and demographic information was obtained from medical records of affected dogs that were evaluated at these clinics. A retrospective case control study was conducted for an additional 49 dogs with blastomycosis that were evaluated at specialty referral centers located in the southern mid-Michigan region. Prevalence rates were calculated for each county, and cases were mapped using geocoding software. Univariable and multivariable analyses were used to identify risk factors for infection. Prevalence rates were ≥100 cases per 100,000 dogs in five counties. Most blastomycosis cases originated from the Upper Peninsula or from a high-density area in the northern Lower Peninsula. Multivariable regression analysis identified travel or residence north of the 45th parallel as a strong risk factor for infection (P < .001). Blastomycosis was uncommon in southern counties. These results refute previous speculations and should be of value to both human and animal health. Given that many heightened risk areas are popular tourist destinations, practitioners across the USA should be mindful of the spatial distribution of blastomycosis in Michigan.</description><subject>Animals</subject><subject>Blastomyces</subject><subject>Blastomycosis - diagnosis</subject><subject>Blastomycosis - epidemiology</subject><subject>Blastomycosis - veterinary</subject><subject>Dog Diseases - epidemiology</subject><subject>Dog Diseases - microbiology</subject><subject>Dogs</subject><subject>Female</subject><subject>Male</subject><subject>Michigan - epidemiology</subject><subject>Original</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Seasons</subject><subject>Surveys and Questionnaires</subject><issn>1369-3786</issn><issn>1460-2709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><sourceid>EIF</sourceid><recordid>eNp9kctKxTAQhoMo3jc-gGQjiFhNmp6m3Qgi3kBRUNdhmk402ibHpBWOT2_kqOjG1QzMN_9cfkK2ODvgrBaHfT877GfvnLMFssqLkmW5ZPViykVZZ0JW5QpZi_GZMS7rXCyTFcGlyGUhV8n9bcA36NBp3KetjUOwzThY7_YpuJYGG1-oAT34EKnxgWpw1iFtOoiD72faRxupdfTa6if7CKnt4e54gywZ6CJufsV18nB2en9ykV3dnF-eHF9lumDVkJkGy6ZtcCLrCkWe84IXkC7SDAE5ahCi0to0sjaslFUBpeAla0RbV8wYALFOjua607HpsdXohgCdmgbbQ5gpD1b9rTj7pB79m0rXl5NqkgR2vwSCfx0xDqq3UWPXgUM_RpULPuGfs_OE7s1RHXyMAc3PGM7Upw0q2aDmNiR4-_diP-j33xOwMwf8OP1P6AO3NpMl</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Shelnutt, Leslie M</creator><creator>Kaneene, John B</creator><creator>Carneiro, Paulo A M</creator><creator>Langlois, Daniel K</creator><general>Oxford University Press</general><scope>TOX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7726-6307</orcidid></search><sort><creationdate>20200701</creationdate><title>Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA</title><author>Shelnutt, Leslie M ; Kaneene, John B ; Carneiro, Paulo A M ; Langlois, Daniel K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-fbe6bdbe5798e3221414a109c0eae1eca338ccfb79f06784a63160b3d980ffaa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Blastomyces</topic><topic>Blastomycosis - diagnosis</topic><topic>Blastomycosis - epidemiology</topic><topic>Blastomycosis - veterinary</topic><topic>Dog Diseases - epidemiology</topic><topic>Dog Diseases - microbiology</topic><topic>Dogs</topic><topic>Female</topic><topic>Male</topic><topic>Michigan - epidemiology</topic><topic>Original</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Seasons</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shelnutt, Leslie M</creatorcontrib><creatorcontrib>Kaneene, John B</creatorcontrib><creatorcontrib>Carneiro, Paulo A M</creatorcontrib><creatorcontrib>Langlois, Daniel K</creatorcontrib><collection>Oxford Journals Open Access Collection</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical mycology (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shelnutt, Leslie M</au><au>Kaneene, John B</au><au>Carneiro, Paulo A M</au><au>Langlois, Daniel K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA</atitle><jtitle>Medical mycology (Oxford)</jtitle><addtitle>Med Mycol</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>58</volume><issue>5</issue><spage>609</spage><epage>616</epage><pages>609-616</pages><issn>1369-3786</issn><eissn>1460-2709</eissn><abstract>Abstract
Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to investigate the prevalence and distribution of canine blastomycosis cases in Michigan and to identify risk factors for infection. Over 200 primary care veterinary clinics throughout the state were surveyed regarding blastomycosis prevalence, and demographic information was obtained from medical records of affected dogs that were evaluated at these clinics. A retrospective case control study was conducted for an additional 49 dogs with blastomycosis that were evaluated at specialty referral centers located in the southern mid-Michigan region. Prevalence rates were calculated for each county, and cases were mapped using geocoding software. Univariable and multivariable analyses were used to identify risk factors for infection. Prevalence rates were ≥100 cases per 100,000 dogs in five counties. Most blastomycosis cases originated from the Upper Peninsula or from a high-density area in the northern Lower Peninsula. Multivariable regression analysis identified travel or residence north of the 45th parallel as a strong risk factor for infection (P < .001). Blastomycosis was uncommon in southern counties. These results refute previous speculations and should be of value to both human and animal health. Given that many heightened risk areas are popular tourist destinations, practitioners across the USA should be mindful of the spatial distribution of blastomycosis in Michigan.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>31732747</pmid><doi>10.1093/mmy/myz110</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-7726-6307</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Animals Blastomyces Blastomycosis - diagnosis Blastomycosis - epidemiology Blastomycosis - veterinary Dog Diseases - epidemiology Dog Diseases - microbiology Dogs Female Male Michigan - epidemiology Original Prevalence Retrospective Studies Risk Factors Seasons Surveys and Questionnaires |
| title | Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA |
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