A Novel Cecropin D-Derived Short Cationic Antimicrobial Peptide Exhibits Antibacterial Activity Against Wild-Type and Multidrug-Resistant Strains of Klebsiella pneumoniae and Pseudomonas aeruginosa

Infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa and Klebsiella pneumoniae are a serious worldwide public health concern due to the ineffectiveness of empirical antibiotic therapy. Therefore, research and the development of new antibiotic alternatives are urgently needed to cont...

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Veröffentlicht in:	Evolutionary bioinformatics online 2020, Vol.16, p.1176934320936266-1176934320936266
Hauptverfasser:	Ocampo-Ibáñez, Iván Darío, Liscano, Yamil, Rivera-Sánchez, Sandra Patricia, Oñate-Garzón, José, Lugo-Guevara, Ashley Dayan, Flórez-Elvira, Liliana Janeth, Lesmes, Maria Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial activity Antibiotics Antimicrobial peptides Antimicrobial Resistance Cationic antimicrobial peptides Cations Cecropin Clinical isolates Erythrocytes Glycerol Klebsiella Klebsiella pneumoniae Membranes Minimum inhibitory concentration Molecular dynamics Multidrug resistance Peptides Phospholipids Pseudomonas aeruginosa Public health Strains (organisms)
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