Aggregation of human mesenchymal stem cells enhances survival and efficacy in stroke treatment

AbstractHuman mesenchymal stem cells (hMSCs) have been shown to enhance stroke lesion recovery by mediating inflammation and tissue repair through secretion of trophic factors. However, low cell survival and reduced primitive stem cell function of culture-expanded hMSCs are the major challenges limi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cytotherapy (Oxford, England) England), 2019-10, Vol.21 (10), p.1033-1048
Hauptverfasser:	Yuan, Xuegang, Rosenberg, Jens T, Liu, Yijun, Grant, Samuel C, Ma, Teng
Format:	Artikel
Sprache:	eng
Schlagworte:	3D aggregation culture Advanced Basic Science human mesenchymal stem cells ischemic stroke metabolic reconfiguration Other PI3K/AKT pathway
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!