SARS-CoV-2 Infection in Patients with Down Syndrome, Congenital Heart Disease, and Pulmonary Hypertension: Is Down Syndrome a Risk Factor?

With increasing information available about the epidemiology, pathophysiology, and management of patients affected with severe acute respiratory syndrome corona virus-2 infection, patients with Down syndrome, congenital heart disease, airway obstruction, and pulmonary hypertension present a unique c...

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Veröffentlicht in:The Journal of pediatrics 2020-10, Vol.225, p.246-248
Hauptverfasser: Krishnan, Usha S., Krishnan, Sankaran S., Jain, Shipra, Chavolla-Calderon, Mara B., Lewis, Matthew, Chung, Wendy K., Rosenzweig, Erika B.
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container_end_page 248
container_issue
container_start_page 246
container_title The Journal of pediatrics
container_volume 225
creator Krishnan, Usha S.
Krishnan, Sankaran S.
Jain, Shipra
Chavolla-Calderon, Mara B.
Lewis, Matthew
Chung, Wendy K.
Rosenzweig, Erika B.
description With increasing information available about the epidemiology, pathophysiology, and management of patients affected with severe acute respiratory syndrome corona virus-2 infection, patients with Down syndrome, congenital heart disease, airway obstruction, and pulmonary hypertension present a unique challenge. This case series describes 3 patients with Down syndrome and respiratory failure secondary to coronavirus infection.
doi_str_mv 10.1016/j.jpeds.2020.06.076
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult
Betacoronavirus
Brief Reports
Child, Preschool
congenital heart disease
Coronavirus Infections - complications
COVID-19
Down syndrome
Down Syndrome - complications
Female
Heart Defects, Congenital - complications
Humans
Hypertension, Pulmonary - complications
Male
obstructive sleep apnea
Pandemics
Pneumonia, Viral - complications
pulmonary hypertension
respiratory failure
Risk Factors
SARS-CoV-2
Young Adult
title SARS-CoV-2 Infection in Patients with Down Syndrome, Congenital Heart Disease, and Pulmonary Hypertension: Is Down Syndrome a Risk Factor?
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