Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study

Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted a...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2020-05, Vol.12 (5), p.e8319
Hauptverfasser: Rajaram, Manju, Malik, Archana, Mohanty Mohapatra, Madhusmita, Vijayageetha, Mathavaswami, Mahesh Babu, Vemuri, Vally, Soundara, Saka, Vinod Kumar
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container_start_page e8319
container_title Curēus (Palo Alto, CA)
container_volume 12
creator Rajaram, Manju
Malik, Archana
Mohanty Mohapatra, Madhusmita
Vijayageetha, Mathavaswami
Mahesh Babu, Vemuri
Vally, Soundara
Saka, Vinod Kumar
description Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.
doi_str_mv 10.7759/cureus.8319
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Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly &gt; 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly &gt;60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.8319</identifier><identifier>PMID: 32607302</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Age groups ; Cavitation ; Cross-sectional studies ; Diabetes ; Epidemiology/Public Health ; Hemoglobin ; Hospitals ; Infectious Disease ; Lungs ; Medical diagnosis ; Patients ; Pulmonology ; Tuberculosis ; X-rays</subject><ispartof>Curēus (Palo Alto, CA), 2020-05, Vol.12 (5), p.e8319</ispartof><rights>Copyright © 2020, Rajaram et al.</rights><rights>Copyright © 2020, Rajaram et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2020, Rajaram et al. 2020 Rajaram et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-dca42ec3ed30e29fae97e86522f2b809434ee73eacae7da663c22ed4f8918d413</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320658/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320658/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32607302$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajaram, Manju</creatorcontrib><creatorcontrib>Malik, Archana</creatorcontrib><creatorcontrib>Mohanty Mohapatra, Madhusmita</creatorcontrib><creatorcontrib>Vijayageetha, Mathavaswami</creatorcontrib><creatorcontrib>Mahesh Babu, Vemuri</creatorcontrib><creatorcontrib>Vally, Soundara</creatorcontrib><creatorcontrib>Saka, Vinod Kumar</creatorcontrib><title>Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly &gt;60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly &gt; 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly &gt;60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. 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Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly &gt; 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly &gt;60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>32607302</pmid><doi>10.7759/cureus.8319</doi><oa>free_for_read</oa></addata></record>
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subjects Age groups
Cavitation
Cross-sectional studies
Diabetes
Epidemiology/Public Health
Hemoglobin
Hospitals
Infectious Disease
Lungs
Medical diagnosis
Patients
Pulmonology
Tuberculosis
X-rays
title Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study
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