Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study
Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted a...
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description | Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals. |
doi_str_mv | 10.7759/cureus.8319 |
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Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.8319</identifier><identifier>PMID: 32607302</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Age groups ; Cavitation ; Cross-sectional studies ; Diabetes ; Epidemiology/Public Health ; Hemoglobin ; Hospitals ; Infectious Disease ; Lungs ; Medical diagnosis ; Patients ; Pulmonology ; Tuberculosis ; X-rays</subject><ispartof>Curēus (Palo Alto, CA), 2020-05, Vol.12 (5), p.e8319</ispartof><rights>Copyright © 2020, Rajaram et al.</rights><rights>Copyright © 2020, Rajaram et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2020, Rajaram et al. 2020 Rajaram et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-dca42ec3ed30e29fae97e86522f2b809434ee73eacae7da663c22ed4f8918d413</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320658/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320658/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32607302$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajaram, Manju</creatorcontrib><creatorcontrib>Malik, Archana</creatorcontrib><creatorcontrib>Mohanty Mohapatra, Madhusmita</creatorcontrib><creatorcontrib>Vijayageetha, Mathavaswami</creatorcontrib><creatorcontrib>Mahesh Babu, Vemuri</creatorcontrib><creatorcontrib>Vally, Soundara</creatorcontrib><creatorcontrib>Saka, Vinod Kumar</creatorcontrib><title>Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.</description><subject>Age groups</subject><subject>Cavitation</subject><subject>Cross-sectional studies</subject><subject>Diabetes</subject><subject>Epidemiology/Public Health</subject><subject>Hemoglobin</subject><subject>Hospitals</subject><subject>Infectious Disease</subject><subject>Lungs</subject><subject>Medical diagnosis</subject><subject>Patients</subject><subject>Pulmonology</subject><subject>Tuberculosis</subject><subject>X-rays</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdks1u1DAUhSMEotXQFXtkiQ0SpDh2JnFYILWhUKQRjJgixCq6Y99MXTnx4J9W83y8GE6nVIWVbZ3PR-faJ8ueF_S4rufNWxkdRn8seNE8yg5ZUYlcFKJ8_GB_kB15f0UpLWjNaE2fZgecVbTmlB1mv1s7bMFpb0die9IaPWoJ5g35BkpbYzfTicCoyALW1kGwbkeW4GDAgM6TUww3iCM5Mwqd2d2SP20cNwkKGsdAfuhwSb7gTRI_aNiM1qMiqwHBkaX1OuhrJMtoBjtCsr6Ia3QymqT4d-SEnFu_1QFMfgrTvdZZ78kKZdCJN2QVoto9y570YDwe3a2z7PvHs4v2PF98_fS5PVnkkvMm5EpCyVByVJwia3rApkZRzRnr2VrQpuQlYs0RJGCtoKq4ZAxV2YumEKos-Cx7v_fdxvWASqbpHJhu6_SQoncWdPevMurLbmOvu5ozWs1FMnh1Z-Dsr4g-dIP2Eo2BEW30HSuLpixoOW8S-vI_9MpGl0a-pUTDxTz94Cx7vafk9C4O-_swBe2mfnT7fnRTPxL94mH-e_ZvG_gfrGO8oA</recordid><startdate>20200527</startdate><enddate>20200527</enddate><creator>Rajaram, Manju</creator><creator>Malik, Archana</creator><creator>Mohanty Mohapatra, Madhusmita</creator><creator>Vijayageetha, Mathavaswami</creator><creator>Mahesh Babu, Vemuri</creator><creator>Vally, Soundara</creator><creator>Saka, Vinod Kumar</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200527</creationdate><title>Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study</title><author>Rajaram, Manju ; Malik, Archana ; Mohanty Mohapatra, Madhusmita ; Vijayageetha, Mathavaswami ; Mahesh Babu, Vemuri ; Vally, Soundara ; Saka, Vinod Kumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-dca42ec3ed30e29fae97e86522f2b809434ee73eacae7da663c22ed4f8918d413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Age groups</topic><topic>Cavitation</topic><topic>Cross-sectional studies</topic><topic>Diabetes</topic><topic>Epidemiology/Public Health</topic><topic>Hemoglobin</topic><topic>Hospitals</topic><topic>Infectious Disease</topic><topic>Lungs</topic><topic>Medical diagnosis</topic><topic>Patients</topic><topic>Pulmonology</topic><topic>Tuberculosis</topic><topic>X-rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rajaram, Manju</creatorcontrib><creatorcontrib>Malik, Archana</creatorcontrib><creatorcontrib>Mohanty Mohapatra, Madhusmita</creatorcontrib><creatorcontrib>Vijayageetha, Mathavaswami</creatorcontrib><creatorcontrib>Mahesh Babu, Vemuri</creatorcontrib><creatorcontrib>Vally, Soundara</creatorcontrib><creatorcontrib>Saka, Vinod Kumar</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajaram, Manju</au><au>Malik, Archana</au><au>Mohanty Mohapatra, Madhusmita</au><au>Vijayageetha, Mathavaswami</au><au>Mahesh Babu, Vemuri</au><au>Vally, Soundara</au><au>Saka, Vinod Kumar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2020-05-27</date><risdate>2020</risdate><volume>12</volume><issue>5</issue><spage>e8319</spage><pages>e8319-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>32607302</pmid><doi>10.7759/cureus.8319</doi><oa>free_for_read</oa></addata></record> |
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subjects | Age groups Cavitation Cross-sectional studies Diabetes Epidemiology/Public Health Hemoglobin Hospitals Infectious Disease Lungs Medical diagnosis Patients Pulmonology Tuberculosis X-rays |
title | Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study |
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