SNHG3 Functions as miRNA Sponge to Promote Breast Cancer Cells Growth Through the Metabolic Reprogramming

Cancer-associated fibroblasts (CAFs) are important ingredient in tumor microenvironment. The dynamic interplay between CAFs and cancer cells plays essential roles during tumor development and progression. However, the mechanisms of intercellular communication between CAFs and cancer cells remain lar...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2020-07, Vol.191 (3), p.1084-1099
Hauptverfasser:	Li, Yan, Zhao, Zhenhui, Liu, Wei, Li, Xun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biotechnology Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Carboxylation Cell growth Cell interactions Cell Line, Tumor Cell proliferation Cell signaling Cell Survival Chemistry Chemistry and Materials Science Disease Progression Exosomes Exosomes - metabolism Female Fibroblasts Fibroblasts - metabolism Gene Expression Regulation, Neoplastic Glycolysis Humans In vivo methods and tests Inflammation MCF-7 Cells Metabolic pathways Metabolism Mice Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Microscopy, Electron, Transmission miRNA Mitochondria Mitochondria - metabolism Neoplasm Transplantation Oxidative phosphorylation Oxygen Consumption Phosphorylation Protein Binding Pyruvate kinase Pyruvate Kinase - genetics Pyruvate Kinase - metabolism Pyruvic acid RNA, Long Noncoding - genetics Transmission electron microscopy Tumor cells Tumors Xenografts Xenotransplantation
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