Elevated Cerebrospinal Fluid Tau Protein Concentrations on Admission Are Associated With Long-term Neurologic and Cognitive Impairment in Ugandan Children With Cerebral Malaria

Abstract Background Elevated concentrations of cerebrospinal fluid (CSF) tau, a marker of axonal injury, have been associated with coma in severe malaria (cerebral malaria [CM]). However, it is unknown whether axonal injury is related to long-term neurologic deficits and cognitive impairment in chil...

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Veröffentlicht in:	Clinical infectious diseases 2020-03, Vol.70 (6), p.1161-1168
Hauptverfasser:	Datta, Dibyadyuti, Conroy, Andrea L, Castelluccio, Peter F, Ssenkusu, John M, Park, Gregory S, Opoka, Robert O, Bangirana, Paul, Idro, Richard, Saykin, Andrew J, John, Chandy C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aftercare and Commentaries Biomarkers Child Cognitive Dysfunction Humans Malaria, Cerebral - complications Patient Discharge tau Proteins Uganda - epidemiology
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