Cytochrome P450-mediated drug interactions in COVID-19 patients: Current findings and possible mechanisms

At the end of 2019, the entire world has witnessed the birth of a new member of coronavirus family in Wuhan, China. Ever since, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has swiftly invaded every corner on the planet. By the end of April 2020, almost 3.5 million cases have bee...

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Veröffentlicht in:	Medical hypotheses 2020-11, Vol.144, p.110033-110033, Article 110033
Hauptverfasser:	El-Ghiaty, Mahmoud A., Shoieb, Sherif M., El-Kadi, Ayman O.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Comorbidity COVID-19 COVID-19 - drug therapy COVID-19 - metabolism Cytochrome P-450 Enzyme System - chemistry Cytochrome P450 Cytokines Cytokines - metabolism Drug interaction Drug Interactions Drug Monitoring Humans Inflammation Interleukin-6 - genetics Liver - injuries Liver - metabolism Metabolism Mice Mice, Knockout Pharmacokinetics SARS-CoV-2 Treatment Outcome Vulnerable Populations
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