Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway

Curcumin, a natural polyphenol antioxidant extracted from the root of turmeric (Curcuma longa), can induce apoptosis and DNA demethylation in several types of cancer cells. However, the mechanism of its anticancer potentials and DNA demethylation effects and the potential relationships between these...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oxidative medicine and cellular longevity 2020, Vol.2020 (2020), p.1-13
Hauptverfasser:	Ma, Libing, He, Xiaoying, Jiang, Xinying, Zhou, Jigang, Liu, Yang, Liu, Ying, Wu, Xian, Tong, Ruiying, Zhang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - drug effects Base Sequence Biotechnology Cancer Cancer cells Cancer therapies Care and treatment Cell Cycle Checkpoints - drug effects Cell Line, Tumor Cell Movement - drug effects Cell Proliferation - drug effects Cloning Curcumin - chemistry Curcumin - pharmacology Cytotoxicity Deoxyribonucleic acid DNA DNA Damage DNA Demethylation - drug effects DNA methylation DNA repair DNA Repair - drug effects Epigenetics Gastric cancer Gene expression Genes Genetic aspects Genome, Human Humans Methylation Methyltransferases Mitochondria - drug effects Mitochondria - metabolism Models, Biological Reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction - drug effects Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - pathology Tumor proteins Tumor Stem Cell Assay Wound healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!