Robust detection of oncometabolic aberrations by 1H–13C heteronuclear single quantum correlation in intact biological specimens

Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted 1 H spectra of intact biological material and limiting diagnostic utility. Here, w...

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Veröffentlicht in:	Communications biology 2020-06, Vol.3 (1), p.328-328, Article 328
Hauptverfasser:	Barekatain, Yasaman, Yan, Victoria C., Arthur, Kenisha, Ackroyd, Jeffrey J., Khadka, Sunada, De Groot, John, Huse, Jason T., Muller, Florian L.
Format:	Artikel
Sprache:	eng
Schlagworte:	101/6 13/106 631/1647/320 631/67/69 64/60 692/308/53/2421 692/699/67/2327 Biology Biomedical and Life Sciences Glioblastoma Life Sciences Metabolites NMR Nuclear magnetic resonance Oncology Precision medicine Spectroscopy Spectrum analysis Tumors Xenografts
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