Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis
Background The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength. Methods Systematic l...
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| Veröffentlicht in: | Supportive care in cancer 2020-08, Vol.28 (8), p.3593-3603 |
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| creator | Hasenoehrl, Timothy Palma, Stefano Ramazanova, Dariga Kölbl, Heinz Dorner, Thomas E. Keilani, Mohammad Crevenna, Richard |
| description | Background
The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.
Methods
Systematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies—both randomized controlled and uncontrolled—which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.
Results
Altogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI − 1.10 [− 2.19, − 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).
Conclusion
RE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it. |
| doi_str_mv | 10.1007/s00520-020-05521-x |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7316683</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A627726413</galeid><sourcerecordid>A627726413</sourcerecordid><originalsourceid>FETCH-LOGICAL-c541t-9ac62e2f639999341565ed9c605399ace4660c208ffa0a2bf2bf0aa4a84075de3</originalsourceid><addsrcrecordid>eNp9UktuFDEQtRCIDIELsEAtsWHTofzv3iBFET8pEhKCtVXjrp446s9g9yQzu9wBTpiT4GZCQhDC5ZKtqlevXNZj7DmHIw5gXycALaCE2bUWvNw-YAuupCytlPVDtoBa8VJJrQ_Yk5TOAbi1WjxmB1IormVlFix8phTShIOngrYUfUhU4NAUy0iYpsLPmXh99T1ShxM1Rbfr12fUUI_XVz-wSLs05fsUfBHpItBlsVk3GfiLo6cJSxyw2-UeT9mjFrtEz27OQ_b13dsvJx_K00_vP54cn5ZeKz6VNXojSLRG1nnJ_E6jqam9AZ0j6EkZA15A1bYIKJZt3oCosFJgdUPykL3Z8643y54aT8MUsXPrGHqMOzdicPczQzhzq_HCWcmNqWQmeHVDEMdvG0qT60Py1HU40LhJTijIVgkxQ1_-BT0fNzEPPKO45cZWIO5QK-zIhaEdc18_k7pjI6wVRvGZ6-gfqGz5r4MfB2pDjt8rEPsCH8eUIrW3M3Jws0DcXiAOZp8F4ra56MWfv3Nb8lsRGSD3gJRTw4ri3Uj_of0J4hfJPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2417167802</pqid></control><display><type>article</type><title>Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Hasenoehrl, Timothy ; Palma, Stefano ; Ramazanova, Dariga ; Kölbl, Heinz ; Dorner, Thomas E. ; Keilani, Mohammad ; Crevenna, Richard</creator><creatorcontrib>Hasenoehrl, Timothy ; Palma, Stefano ; Ramazanova, Dariga ; Kölbl, Heinz ; Dorner, Thomas E. ; Keilani, Mohammad ; Crevenna, Richard</creatorcontrib><description>Background
The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.
Methods
Systematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies—both randomized controlled and uncontrolled—which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.
Results
Altogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI − 1.10 [− 2.19, − 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).
Conclusion
RE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it.</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-020-05521-x</identifier><identifier>PMID: 32415386</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Analysis ; Breast cancer ; Breast Cancer Lymphedema - epidemiology ; Cancer Survivors ; Electric Impedance ; Exercise ; Exercise therapy ; Female ; Football (College) ; Humans ; Lymphedema ; Medicine ; Medicine & Public Health ; Meta-analysis ; Nursing ; Nursing Research ; Oncology ; Pain Medicine ; Randomized Controlled Trials as Topic ; Rehabilitation Medicine ; Resistance Training - adverse effects ; Resistance Training - methods ; Resistance Training - statistics & numerical data ; Review ; Review Article ; Strength training ; Systematic review</subject><ispartof>Supportive care in cancer, 2020-08, Vol.28 (8), p.3593-3603</ispartof><rights>The Author(s) 2020</rights><rights>COPYRIGHT 2020 Springer</rights><rights>The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c541t-9ac62e2f639999341565ed9c605399ace4660c208ffa0a2bf2bf0aa4a84075de3</citedby><cites>FETCH-LOGICAL-c541t-9ac62e2f639999341565ed9c605399ace4660c208ffa0a2bf2bf0aa4a84075de3</cites><orcidid>0000-0001-8263-6720 ; 0000-0002-9177-0101</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-020-05521-x$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-020-05521-x$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32415386$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hasenoehrl, Timothy</creatorcontrib><creatorcontrib>Palma, Stefano</creatorcontrib><creatorcontrib>Ramazanova, Dariga</creatorcontrib><creatorcontrib>Kölbl, Heinz</creatorcontrib><creatorcontrib>Dorner, Thomas E.</creatorcontrib><creatorcontrib>Keilani, Mohammad</creatorcontrib><creatorcontrib>Crevenna, Richard</creatorcontrib><title>Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description>Background
The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.
Methods
Systematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies—both randomized controlled and uncontrolled—which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.
Results
Altogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI − 1.10 [− 2.19, − 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).
Conclusion
RE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it.</description><subject>Analysis</subject><subject>Breast cancer</subject><subject>Breast Cancer Lymphedema - epidemiology</subject><subject>Cancer Survivors</subject><subject>Electric Impedance</subject><subject>Exercise</subject><subject>Exercise therapy</subject><subject>Female</subject><subject>Football (College)</subject><subject>Humans</subject><subject>Lymphedema</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Meta-analysis</subject><subject>Nursing</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Pain Medicine</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Rehabilitation Medicine</subject><subject>Resistance Training - adverse effects</subject><subject>Resistance Training - methods</subject><subject>Resistance Training - statistics & numerical data</subject><subject>Review</subject><subject>Review Article</subject><subject>Strength training</subject><subject>Systematic review</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9UktuFDEQtRCIDIELsEAtsWHTofzv3iBFET8pEhKCtVXjrp446s9g9yQzu9wBTpiT4GZCQhDC5ZKtqlevXNZj7DmHIw5gXycALaCE2bUWvNw-YAuupCytlPVDtoBa8VJJrQ_Yk5TOAbi1WjxmB1IormVlFix8phTShIOngrYUfUhU4NAUy0iYpsLPmXh99T1ShxM1Rbfr12fUUI_XVz-wSLs05fsUfBHpItBlsVk3GfiLo6cJSxyw2-UeT9mjFrtEz27OQ_b13dsvJx_K00_vP54cn5ZeKz6VNXojSLRG1nnJ_E6jqam9AZ0j6EkZA15A1bYIKJZt3oCosFJgdUPykL3Z8643y54aT8MUsXPrGHqMOzdicPczQzhzq_HCWcmNqWQmeHVDEMdvG0qT60Py1HU40LhJTijIVgkxQ1_-BT0fNzEPPKO45cZWIO5QK-zIhaEdc18_k7pjI6wVRvGZ6-gfqGz5r4MfB2pDjt8rEPsCH8eUIrW3M3Jws0DcXiAOZp8F4ra56MWfv3Nb8lsRGSD3gJRTw4ri3Uj_of0J4hfJPA</recordid><startdate>20200801</startdate><enddate>20200801</enddate><creator>Hasenoehrl, Timothy</creator><creator>Palma, Stefano</creator><creator>Ramazanova, Dariga</creator><creator>Kölbl, Heinz</creator><creator>Dorner, Thomas E.</creator><creator>Keilani, Mohammad</creator><creator>Crevenna, Richard</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8263-6720</orcidid><orcidid>https://orcid.org/0000-0002-9177-0101</orcidid></search><sort><creationdate>20200801</creationdate><title>Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis</title><author>Hasenoehrl, Timothy ; 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The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.
Methods
Systematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies—both randomized controlled and uncontrolled—which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.
Results
Altogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI − 1.10 [− 2.19, − 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).
Conclusion
RE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32415386</pmid><doi>10.1007/s00520-020-05521-x</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-8263-6720</orcidid><orcidid>https://orcid.org/0000-0002-9177-0101</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Supportive care in cancer, 2020-08, Vol.28 (8), p.3593-3603 |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Analysis Breast cancer Breast Cancer Lymphedema - epidemiology Cancer Survivors Electric Impedance Exercise Exercise therapy Female Football (College) Humans Lymphedema Medicine Medicine & Public Health Meta-analysis Nursing Nursing Research Oncology Pain Medicine Randomized Controlled Trials as Topic Rehabilitation Medicine Resistance Training - adverse effects Resistance Training - methods Resistance Training - statistics & numerical data Review Review Article Strength training Systematic review |
| title | Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis |
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