Interferon-Dependent and Respiratory Virus-Specific Interference in Dual Infections of Airway Epithelia

Many respiratory viruses cocirculate in the population and multiple infections are commonly reported. The clinical impact of coinfection is unclear and may vary depending on the viral couples involved. Using three-dimensional reconstituted human airway epithelia and clinical viral strains, we invest...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.10246-10246, Article 10246
Hauptverfasser:	Essaidi-Laziosi, Manel, Geiser, Johan, Huang, Song, Constant, Samuel, Kaiser, Laurent, Tapparel, Caroline
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/596/2553 631/326/596/2557 631/326/596/2558 Cells, Cultured Coinfection - virology Epithelial Cells - immunology Epithelial Cells - virology Humanities and Social Sciences Humans Infections Inflammation Influenza Influenza A virus - immunology Influenza A virus - physiology Innate immunity Interferon Interferon-gamma - metabolism Interferons - metabolism Interferons - pharmacology Mucosa multidisciplinary Respiratory Mucosa - cytology Respiratory Mucosa - immunology Respiratory Mucosa - virology Respiratory syncytial virus Respiratory Syncytial Virus, Human - immunology Respiratory Syncytial Virus, Human - physiology Respiratory tract Respiratory Tract Infections - virology Rhinovirus Rhinovirus - immunology Rhinovirus - physiology Science Science (multidisciplinary) Virus Internalization Virus Replication Viruses α-Interferon
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