Critical role of OX40 in drug‐induced acute liver injury

Background and Purpose The innate and adaptive immune systems both play important roles in drug‐induced liver injury (DILI). However, the crosstalk between the innate and adaptive immunity in DILI is largely unknown. Extensive crosstalk is likely mandated by co‐stimulatory interactions between these...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 2020-07, Vol.177 (14), p.3183-3196
Hauptverfasser:	Zhang, Chunpan, Jin, Hua, Wang, Yan, Li, Changying, Zhao, Xinyan, Li, Yanmeng, Shi, Wen, Tian, Yue, Xu, Hufeng, Tian, Dan, Liu, Kai, Jia, Jidong, Sun, Guangyong, Zhang, Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Adaptive immunity Adoptive transfer Analgesics Animals Bile Carbon tetrachloride CCL4 protein CD4 antigen Chemical and Drug Induced Liver Injury D-Galactosamine Galactosamine Gene regulation Helper cells Hepatocytes Humans Infiltration Inflammation Lipopolysaccharides Liver Lymphocytes T Macrophages Mice Mice, Inbred C57BL Mice, Knockout Paracetamol RAG1 protein Receptors, OX40 Research Paper Research Papers Rodents Therapeutic applications Tumor necrosis factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!