Copper Coordination Compounds as Biologically Active Agents

Copper-containing coordination compounds attract wide attention due to the redox activity and biogenicity of copper ions, providing multiple pathways of biological activity. The pharmacological properties of metal complexes can be fine-tuned by varying the nature of the ligand and donor atoms. Coppe...

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Veröffentlicht in:	International journal of molecular sciences 2020-05, Vol.21 (11), p.3965
Hauptverfasser:	Krasnovskaya, Olga, Naumov, Alexey, Guk, Dmitry, Gorelkin, Peter, Erofeev, Alexander, Beloglazkina, Elena, Majouga, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Amyloid beta-Peptides - chemistry Animals Anti-Infective Agents - therapeutic use Antineoplastic Agents - therapeutic use Biological Factors - chemistry Cell Line, Tumor Copper - chemistry Drug Design Drug Evaluation, Preclinical Flow Cytometry HEK293 Cells Humans Inhibitory Concentration 50 Ions Isotopes - chemistry Ligands MCF-7 Cells Mycobacterium tuberculosis Oxidation-Reduction Positron-Emission Tomography Review Spectrophotometry Tetrazolium Salts - pharmacology Thiazoles - pharmacology Tuberculosis - drug therapy
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