Association of the methylene-tetrahydrofolate reductase gene rs1801133 C677T variant with serum homocysteine levels, and the severity of coronary artery disease

This study aimed to investigate whether the single nucleotide polymorphism C677T (rs1801133) of the methylene-tetrahydrofolate reductase (MTHFR) gene was associated with the risk of coronary artery disease (CAD) and circulating homocysteine (Hcy) levels in Tunisian population. 310 angiografically di...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.10064-10064, Article 10064
Hauptverfasser:	Bouzidi, Nadia, Hassine, Majed, Fodha, Hajer, Ben Messaoud, Mejdi, Maatouk, Faouzi, Gamra, Habib, Ferchichi, Salima
Format:	Artikel
Sprache:	eng
Schlagworte:	631/45/147 692/4019/2776 692/4019/592/2727 692/53 Adult Aged Alleles Cardiovascular disease Case-Control Studies Coronary artery Coronary Artery Disease - blood Coronary Artery Disease - genetics Coronary vessels Female Gene polymorphism Genetic Association Studies Genetic Predisposition to Disease Genotype Health risk assessment Heart diseases Homocysteine Homocysteine - blood Humanities and Social Sciences Humans Hyperhomocysteinemia Male Methylenetetrahydrofolate reductase Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged multidisciplinary Polymorphism Polymorphism, Single Nucleotide ROC Curve Science Science (multidisciplinary) Severity of Illness Index Single-nucleotide polymorphism Tetrahydrofolic acid Tunisia Young Adult
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