Recommendations for the use of mathematical modelling to support decision‐making on integration of non‐communicable diseases into HIV care

Introduction Integrating services for non‐communicable diseases (NCDs) into existing primary care platforms such as HIV programmes has been recommended as a way of strengthening health systems, reducing redundancies and leveraging existing systems to rapidly scale‐up underdeveloped programmes. Mathe...

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Veröffentlicht in:Journal of the International AIDS Society 2020-06, Vol.23 (SI1), p.e25505-n/a
Hauptverfasser: Kibachio, Joseph, Mwenda, Valerian, Ombiro, Oren, Kamano, Jamima H, Perez‐Guzman, Pablo N, Mutai, Kennedy K, Guessous, Idris, Beran, David, Kasaie, Paratsu, Weir, Brian, Beecroft, Blythe, Kilonzo, Nduku, Kupfer, Linda, Smit, Mikaela
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container_issue SI1
container_start_page e25505
container_title Journal of the International AIDS Society
container_volume 23
creator Kibachio, Joseph
Mwenda, Valerian
Ombiro, Oren
Kamano, Jamima H
Perez‐Guzman, Pablo N
Mutai, Kennedy K
Guessous, Idris
Beran, David
Kasaie, Paratsu
Weir, Brian
Beecroft, Blythe
Kilonzo, Nduku
Kupfer, Linda
Smit, Mikaela
description Introduction Integrating services for non‐communicable diseases (NCDs) into existing primary care platforms such as HIV programmes has been recommended as a way of strengthening health systems, reducing redundancies and leveraging existing systems to rapidly scale‐up underdeveloped programmes. Mathematical modelling provides a powerful tool to address questions around priorities, optimization and implementation of such programmes. In this study, we examine the case for NCD‐HIV integration, use Kenya as a case‐study to highlight how modelling has supported wider policy formulation and decision‐making in healthcare and to collate stakeholders’ recommendations on use of models for NCD‐HIV integration decision‐making. Discussion Across Africa, NCDs are increasingly posing challenges for health systems, which historically focused on the care of acute and infectious conditions. Pilot programmes using integrated care services have generated advantages for both provider and user, been cost‐effective, practical and achieve rapid coverage scale‐up. The shared chronic nature of NCDs and HIV means that many operational approaches and infrastructure developed for HIV programmes apply to NCDs, suggesting this to be a cost‐effective and sustainable policy option for countries with large HIV programmes and small, un‐resourced NCD programmes. However, the vertical nature of current disease programmes, policy financing and operations operate as barriers to NCD‐HIV integration. Modelling has successfully been used to inform health decision‐making across a number of disease areas and in a number of ways. Examples from Kenya include (i) estimating current and future disease burden to set priorities for public health interventions, (ii) forecasting the requisite investments by government, (iii) comparing the impact of different integration approaches, (iv) performing cost‐benefit analysis for integration and (v) evaluating health system capacity needs. Conclusions Modelling can and should play an integral part in the decision‐making processes for health in general and NCD‐HIV integration specifically. It is especially useful where little data is available. The successful use of modelling to inform decision‐making will depend on several factors including policy makers’ comfort with and understanding of models and their uncertainties, modellers understanding of national priorities, funding opportunities and building local modelling capacity to ensure sustainability.
doi_str_mv 10.1002/jia2.25505
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Mathematical modelling provides a powerful tool to address questions around priorities, optimization and implementation of such programmes. In this study, we examine the case for NCD‐HIV integration, use Kenya as a case‐study to highlight how modelling has supported wider policy formulation and decision‐making in healthcare and to collate stakeholders’ recommendations on use of models for NCD‐HIV integration decision‐making. Discussion Across Africa, NCDs are increasingly posing challenges for health systems, which historically focused on the care of acute and infectious conditions. Pilot programmes using integrated care services have generated advantages for both provider and user, been cost‐effective, practical and achieve rapid coverage scale‐up. The shared chronic nature of NCDs and HIV means that many operational approaches and infrastructure developed for HIV programmes apply to NCDs, suggesting this to be a cost‐effective and sustainable policy option for countries with large HIV programmes and small, un‐resourced NCD programmes. However, the vertical nature of current disease programmes, policy financing and operations operate as barriers to NCD‐HIV integration. Modelling has successfully been used to inform health decision‐making across a number of disease areas and in a number of ways. Examples from Kenya include (i) estimating current and future disease burden to set priorities for public health interventions, (ii) forecasting the requisite investments by government, (iii) comparing the impact of different integration approaches, (iv) performing cost‐benefit analysis for integration and (v) evaluating health system capacity needs. Conclusions Modelling can and should play an integral part in the decision‐making processes for health in general and NCD‐HIV integration specifically. It is especially useful where little data is available. The successful use of modelling to inform decision‐making will depend on several factors including policy makers’ comfort with and understanding of models and their uncertainties, modellers understanding of national priorities, funding opportunities and building local modelling capacity to ensure sustainability.</description><identifier>ISSN: 1758-2652</identifier><identifier>EISSN: 1758-2652</identifier><identifier>DOI: 10.1002/jia2.25505</identifier><identifier>PMID: 32562338</identifier><language>eng</language><publisher>Switzerland: International AIDS Society</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Analysis ; Care and treatment ; Childrens health ; Chronic illnesses ; Communicable diseases ; Cost control ; Decision Making ; Delivery of Health Care ; Delivery of Health Care, Integrated ; Diabetes ; Disease prevention ; Expenditures ; Government Programs ; Health aspects ; HIV ; HIV infection ; HIV Infections - therapy ; Human immunodeficiency virus ; Humans ; Hypertension ; Infectious diseases ; Infrastructure ; Integrated delivery networks ; integration ; Kenya ; Laboratories ; Management ; Maternal &amp; child health ; Mathematical models ; Medical research ; modelling ; Models, Biological ; Models, Theoretical ; Mortality ; Noncommunicable Diseases - therapy ; non‐communicable diseases ; Optimization ; policy ; Population ; Primary care ; Primary Health Care ; Risk factors ; Supplement ; Supply chains</subject><ispartof>Journal of the International AIDS Society, 2020-06, Vol.23 (SI1), p.e25505-n/a</ispartof><rights>2020 The Authors. Journal of the International AIDS Society published by John Wiley &amp; Sons Ltd on behalf of the International AIDS Society.</rights><rights>COPYRIGHT 2020 International AIDS Society</rights><rights>COPYRIGHT 2020 John Wiley &amp; Sons, Inc.</rights><rights>2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c7485-94d107a2a3958d5601ebe80724de36dcd3f206a95aa0dfd611a707a9e22faca03</citedby><cites>FETCH-LOGICAL-c7485-94d107a2a3958d5601ebe80724de36dcd3f206a95aa0dfd611a707a9e22faca03</cites><orcidid>0000-0001-8530-748X ; 0000-0002-6886-6818 ; 0000-0002-3744-9501</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305412/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305412/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1417,11562,27924,27925,45574,45575,46052,46476,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32562338$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kibachio, Joseph</creatorcontrib><creatorcontrib>Mwenda, Valerian</creatorcontrib><creatorcontrib>Ombiro, Oren</creatorcontrib><creatorcontrib>Kamano, Jamima H</creatorcontrib><creatorcontrib>Perez‐Guzman, Pablo N</creatorcontrib><creatorcontrib>Mutai, Kennedy K</creatorcontrib><creatorcontrib>Guessous, Idris</creatorcontrib><creatorcontrib>Beran, David</creatorcontrib><creatorcontrib>Kasaie, Paratsu</creatorcontrib><creatorcontrib>Weir, Brian</creatorcontrib><creatorcontrib>Beecroft, Blythe</creatorcontrib><creatorcontrib>Kilonzo, Nduku</creatorcontrib><creatorcontrib>Kupfer, Linda</creatorcontrib><creatorcontrib>Smit, Mikaela</creatorcontrib><title>Recommendations for the use of mathematical modelling to support decision‐making on integration of non‐communicable diseases into HIV care</title><title>Journal of the International AIDS Society</title><addtitle>J Int AIDS Soc</addtitle><description>Introduction Integrating services for non‐communicable diseases (NCDs) into existing primary care platforms such as HIV programmes has been recommended as a way of strengthening health systems, reducing redundancies and leveraging existing systems to rapidly scale‐up underdeveloped programmes. Mathematical modelling provides a powerful tool to address questions around priorities, optimization and implementation of such programmes. In this study, we examine the case for NCD‐HIV integration, use Kenya as a case‐study to highlight how modelling has supported wider policy formulation and decision‐making in healthcare and to collate stakeholders’ recommendations on use of models for NCD‐HIV integration decision‐making. Discussion Across Africa, NCDs are increasingly posing challenges for health systems, which historically focused on the care of acute and infectious conditions. Pilot programmes using integrated care services have generated advantages for both provider and user, been cost‐effective, practical and achieve rapid coverage scale‐up. The shared chronic nature of NCDs and HIV means that many operational approaches and infrastructure developed for HIV programmes apply to NCDs, suggesting this to be a cost‐effective and sustainable policy option for countries with large HIV programmes and small, un‐resourced NCD programmes. However, the vertical nature of current disease programmes, policy financing and operations operate as barriers to NCD‐HIV integration. Modelling has successfully been used to inform health decision‐making across a number of disease areas and in a number of ways. Examples from Kenya include (i) estimating current and future disease burden to set priorities for public health interventions, (ii) forecasting the requisite investments by government, (iii) comparing the impact of different integration approaches, (iv) performing cost‐benefit analysis for integration and (v) evaluating health system capacity needs. Conclusions Modelling can and should play an integral part in the decision‐making processes for health in general and NCD‐HIV integration specifically. It is especially useful where little data is available. 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child health</subject><subject>Mathematical models</subject><subject>Medical research</subject><subject>modelling</subject><subject>Models, Biological</subject><subject>Models, Theoretical</subject><subject>Mortality</subject><subject>Noncommunicable Diseases - therapy</subject><subject>non‐communicable diseases</subject><subject>Optimization</subject><subject>policy</subject><subject>Population</subject><subject>Primary care</subject><subject>Primary Health Care</subject><subject>Risk factors</subject><subject>Supplement</subject><subject>Supply chains</subject><issn>1758-2652</issn><issn>1758-2652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqNk1GL1DAQgIso3nn64g-QgCAi7JpMm7R9EZZDvZUDQdTXkE2mu1nbZK9plXvzF4i_0V9iunseXVmWo9CmnW--ScpMkjxldMoohddrq2AKnFN-LzllOS8mIDjcH61PkkchrCkVUGTlw-QkBS4gTYvT5Ncn1L5p0BnVWe8CqXxLuhWSPiDxFWlUfIk3q1VNGm-wrq1bks6T0G82vu2IQW1DTP3z83ejvg1B74h1HS7brXKwuG14KNS7aFrUSIwNqAKGAfXkYv6VaNXi4-RBpeqAT26eZ8mXd28_n19MLj--n5_PLic6zwo-KTPDaK5ApSUvDBeU4QILmkNmMBVGm7QCKlTJlaKmMoIxlUe-RIBKaUXTs-TNzrvpFw0aja5rVS03rW1Uey29snI_4uxKLv13maeUZwyi4OWNoPVXPYZONjbo-HeUQ98HCRnjUJZClBF9_h-69n3r4vEixaEQNMvEcYplJfBiTC1VjdK6ysfd6aG0nOVAIecZ0KOUgDIWFCmP1OQAtUSH8cDeYWXj5z3rXfixf3qAj5fBxuqDBe6UMK7wYpSwQlV3q-DrftvJ--aj4Nj4agfq1ofQYnXbEozKYdjkMGxyO2wRfjZuolv033RFgO2AH3Hj10dU8sN8BjvpX8qnMjY</recordid><startdate>202006</startdate><enddate>202006</enddate><creator>Kibachio, Joseph</creator><creator>Mwenda, Valerian</creator><creator>Ombiro, Oren</creator><creator>Kamano, Jamima H</creator><creator>Perez‐Guzman, Pablo N</creator><creator>Mutai, Kennedy K</creator><creator>Guessous, Idris</creator><creator>Beran, David</creator><creator>Kasaie, Paratsu</creator><creator>Weir, Brian</creator><creator>Beecroft, Blythe</creator><creator>Kilonzo, Nduku</creator><creator>Kupfer, Linda</creator><creator>Smit, Mikaela</creator><general>International AIDS Society</general><general>John Wiley &amp; 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Mwenda, Valerian ; Ombiro, Oren ; Kamano, Jamima H ; Perez‐Guzman, Pablo N ; Mutai, Kennedy K ; Guessous, Idris ; Beran, David ; Kasaie, Paratsu ; Weir, Brian ; Beecroft, Blythe ; Kilonzo, Nduku ; Kupfer, Linda ; Smit, Mikaela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c7485-94d107a2a3958d5601ebe80724de36dcd3f206a95aa0dfd611a707a9e22faca03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Analysis</topic><topic>Care and treatment</topic><topic>Childrens health</topic><topic>Chronic illnesses</topic><topic>Communicable diseases</topic><topic>Cost control</topic><topic>Decision Making</topic><topic>Delivery of Health Care</topic><topic>Delivery of Health Care, Integrated</topic><topic>Diabetes</topic><topic>Disease prevention</topic><topic>Expenditures</topic><topic>Government Programs</topic><topic>Health aspects</topic><topic>HIV</topic><topic>HIV infection</topic><topic>HIV Infections - therapy</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Infectious diseases</topic><topic>Infrastructure</topic><topic>Integrated delivery networks</topic><topic>integration</topic><topic>Kenya</topic><topic>Laboratories</topic><topic>Management</topic><topic>Maternal &amp; child health</topic><topic>Mathematical models</topic><topic>Medical research</topic><topic>modelling</topic><topic>Models, Biological</topic><topic>Models, Theoretical</topic><topic>Mortality</topic><topic>Noncommunicable Diseases - therapy</topic><topic>non‐communicable diseases</topic><topic>Optimization</topic><topic>policy</topic><topic>Population</topic><topic>Primary care</topic><topic>Primary Health Care</topic><topic>Risk factors</topic><topic>Supplement</topic><topic>Supply chains</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kibachio, Joseph</creatorcontrib><creatorcontrib>Mwenda, Valerian</creatorcontrib><creatorcontrib>Ombiro, Oren</creatorcontrib><creatorcontrib>Kamano, Jamima H</creatorcontrib><creatorcontrib>Perez‐Guzman, Pablo N</creatorcontrib><creatorcontrib>Mutai, Kennedy K</creatorcontrib><creatorcontrib>Guessous, Idris</creatorcontrib><creatorcontrib>Beran, David</creatorcontrib><creatorcontrib>Kasaie, Paratsu</creatorcontrib><creatorcontrib>Weir, Brian</creatorcontrib><creatorcontrib>Beecroft, Blythe</creatorcontrib><creatorcontrib>Kilonzo, Nduku</creatorcontrib><creatorcontrib>Kupfer, Linda</creatorcontrib><creatorcontrib>Smit, Mikaela</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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Mathematical modelling provides a powerful tool to address questions around priorities, optimization and implementation of such programmes. In this study, we examine the case for NCD‐HIV integration, use Kenya as a case‐study to highlight how modelling has supported wider policy formulation and decision‐making in healthcare and to collate stakeholders’ recommendations on use of models for NCD‐HIV integration decision‐making. Discussion Across Africa, NCDs are increasingly posing challenges for health systems, which historically focused on the care of acute and infectious conditions. Pilot programmes using integrated care services have generated advantages for both provider and user, been cost‐effective, practical and achieve rapid coverage scale‐up. The shared chronic nature of NCDs and HIV means that many operational approaches and infrastructure developed for HIV programmes apply to NCDs, suggesting this to be a cost‐effective and sustainable policy option for countries with large HIV programmes and small, un‐resourced NCD programmes. However, the vertical nature of current disease programmes, policy financing and operations operate as barriers to NCD‐HIV integration. Modelling has successfully been used to inform health decision‐making across a number of disease areas and in a number of ways. Examples from Kenya include (i) estimating current and future disease burden to set priorities for public health interventions, (ii) forecasting the requisite investments by government, (iii) comparing the impact of different integration approaches, (iv) performing cost‐benefit analysis for integration and (v) evaluating health system capacity needs. Conclusions Modelling can and should play an integral part in the decision‐making processes for health in general and NCD‐HIV integration specifically. It is especially useful where little data is available. The successful use of modelling to inform decision‐making will depend on several factors including policy makers’ comfort with and understanding of models and their uncertainties, modellers understanding of national priorities, funding opportunities and building local modelling capacity to ensure sustainability.</abstract><cop>Switzerland</cop><pub>International AIDS Society</pub><pmid>32562338</pmid><doi>10.1002/jia2.25505</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-8530-748X</orcidid><orcidid>https://orcid.org/0000-0002-6886-6818</orcidid><orcidid>https://orcid.org/0000-0002-3744-9501</orcidid><oa>free_for_read</oa></addata></record>
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subjects Acquired immune deficiency syndrome
AIDS
Analysis
Care and treatment
Childrens health
Chronic illnesses
Communicable diseases
Cost control
Decision Making
Delivery of Health Care
Delivery of Health Care, Integrated
Diabetes
Disease prevention
Expenditures
Government Programs
Health aspects
HIV
HIV infection
HIV Infections - therapy
Human immunodeficiency virus
Humans
Hypertension
Infectious diseases
Infrastructure
Integrated delivery networks
integration
Kenya
Laboratories
Management
Maternal & child health
Mathematical models
Medical research
modelling
Models, Biological
Models, Theoretical
Mortality
Noncommunicable Diseases - therapy
non‐communicable diseases
Optimization
policy
Population
Primary care
Primary Health Care
Risk factors
Supplement
Supply chains
title Recommendations for the use of mathematical modelling to support decision‐making on integration of non‐communicable diseases into HIV care
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