Opioid system modulation with buprenorphine/samidorphan combination for major depressive disorder: two randomized controlled studies

The endogenous opioid system is thought to play an important role in the regulation of mood. Buprenorphine/samidorphan (BUP/SAM) combination is an investigational opioid system modulator for adjunctive treatment of major depressive disorder (MDD). To confirm results from early studies, we report the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular psychiatry 2020-07, Vol.25 (7), p.1580-1591
Hauptverfasser:	Fava, Maurizio, Thase, Michael E., Trivedi, Madhukar H., Ehrich, Elliot, Martin, William F., Memisoglu, Asli, Nangia, Narinder, Stanford, Arielle D., Yu, Miao, Pathak, Sanjeev
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378 692/699/476/1414 Abuse Adverse events Analgesics, Opioid - therapeutic use Antidepressants Antidepressive Agents - therapeutic use Behavioral Sciences Biological Psychology Buprenorphine Buprenorphine - therapeutic use Care and treatment Constipation Depressive Disorder, Major - drug therapy Depressive Disorder, Major - psychology Double-Blind Method Drug Therapy, Combination Female Humans Laws, regulations and rules Major depressive disorder Male Medical research Medicine Medicine & Public Health Medicine, Experimental Mental depression Middle Aged Mood Naltrexone - analogs & derivatives Naltrexone - therapeutic use Narcotics Nausea Neurosciences Opioids Pharmacotherapy Placebos Psychiatry Treatment Outcome Vomiting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!