The association of lung ultrasound images with COVID‐19 infection in an emergency room cohort

Summary Lung ultrasound could facilitate the triage of patients with suspected COVID‐19 infection admitted to the emergency room. We developed a predictive model for COVID‐19 diagnosis based on lung ultrasound and clinical features. We used ultrasound to image the lung bilaterally at two anterior si...

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Veröffentlicht in:Anaesthesia 2020-12, Vol.75 (12), p.1620-1625
Hauptverfasser: Bar, S., Lecourtois, A., Diouf, M., Goldberg, E., Bourbon, C., Arnaud, E., Domisse, L., Dupont, H., Gosset, P.
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container_end_page 1625
container_issue 12
container_start_page 1620
container_title Anaesthesia
container_volume 75
creator Bar, S.
Lecourtois, A.
Diouf, M.
Goldberg, E.
Bourbon, C.
Arnaud, E.
Domisse, L.
Dupont, H.
Gosset, P.
description Summary Lung ultrasound could facilitate the triage of patients with suspected COVID‐19 infection admitted to the emergency room. We developed a predictive model for COVID‐19 diagnosis based on lung ultrasound and clinical features. We used ultrasound to image the lung bilaterally at two anterior sites, one and two hands below each clavicle, and a posterolateral site that was the posterior transverse continuation from the lower anterior site. We studied 100 patients, 31 of whom had a COVID‐19 positive reverse transcriptase polymerase chain reaction. A positive test was independently associated with: quick sequential organ failure assessment score ≥1; ≥3 B‐lines at the upper site; consolidation and thickened pleura at the lower site; and thickened pleura line at the posterolateral site. The model discrimination was an area (95%CI) under the receiver operating characteristic curve of 0.82 (0.75–0.90). The characteristics (95%CI) of the model’s diagnostic threshold, applied to the population from which it was derived, were: sensitivity, 97% (83–100%); specificity, 62% (50–74%); positive predictive value, 54% (41–98%); and negative predictive value, 98% (88–99%). This model may facilitate triage of patients with suspected COVID‐19 infection admitted to the emergency room.
doi_str_mv 10.1111/anae.15175
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We developed a predictive model for COVID‐19 diagnosis based on lung ultrasound and clinical features. We used ultrasound to image the lung bilaterally at two anterior sites, one and two hands below each clavicle, and a posterolateral site that was the posterior transverse continuation from the lower anterior site. We studied 100 patients, 31 of whom had a COVID‐19 positive reverse transcriptase polymerase chain reaction. A positive test was independently associated with: quick sequential organ failure assessment score ≥1; ≥3 B‐lines at the upper site; consolidation and thickened pleura at the lower site; and thickened pleura line at the posterolateral site. The model discrimination was an area (95%CI) under the receiver operating characteristic curve of 0.82 (0.75–0.90). The characteristics (95%CI) of the model’s diagnostic threshold, applied to the population from which it was derived, were: sensitivity, 97% (83–100%); specificity, 62% (50–74%); positive predictive value, 54% (41–98%); and negative predictive value, 98% (88–99%). 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We developed a predictive model for COVID‐19 diagnosis based on lung ultrasound and clinical features. We used ultrasound to image the lung bilaterally at two anterior sites, one and two hands below each clavicle, and a posterolateral site that was the posterior transverse continuation from the lower anterior site. We studied 100 patients, 31 of whom had a COVID‐19 positive reverse transcriptase polymerase chain reaction. A positive test was independently associated with: quick sequential organ failure assessment score ≥1; ≥3 B‐lines at the upper site; consolidation and thickened pleura at the lower site; and thickened pleura line at the posterolateral site. The model discrimination was an area (95%CI) under the receiver operating characteristic curve of 0.82 (0.75–0.90). The characteristics (95%CI) of the model’s diagnostic threshold, applied to the population from which it was derived, were: sensitivity, 97% (83–100%); specificity, 62% (50–74%); positive predictive value, 54% (41–98%); and negative predictive value, 98% (88–99%). 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We developed a predictive model for COVID‐19 diagnosis based on lung ultrasound and clinical features. We used ultrasound to image the lung bilaterally at two anterior sites, one and two hands below each clavicle, and a posterolateral site that was the posterior transverse continuation from the lower anterior site. We studied 100 patients, 31 of whom had a COVID‐19 positive reverse transcriptase polymerase chain reaction. A positive test was independently associated with: quick sequential organ failure assessment score ≥1; ≥3 B‐lines at the upper site; consolidation and thickened pleura at the lower site; and thickened pleura line at the posterolateral site. The model discrimination was an area (95%CI) under the receiver operating characteristic curve of 0.82 (0.75–0.90). The characteristics (95%CI) of the model’s diagnostic threshold, applied to the population from which it was derived, were: sensitivity, 97% (83–100%); specificity, 62% (50–74%); positive predictive value, 54% (41–98%); and negative predictive value, 98% (88–99%). This model may facilitate triage of patients with suspected COVID‐19 infection admitted to the emergency room.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>32520406</pmid><doi>10.1111/anae.15175</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-5644-3412</orcidid><orcidid>https://orcid.org/0000-0002-4630-5833</orcidid><orcidid>https://orcid.org/0000-0001-9528-2669</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Area Under Curve
Clavicle
Cohort Studies
Coronavirus Infections - diagnosis
Coronavirus Infections - diagnostic imaging
COVID-19
Diagnostic systems
Emergencies
Emergency medical care
Emergency Medical Services
Emergency Service, Hospital - organization & administration
Emergency Service, Hospital - statistics & numerical data
Female
Humans
Infections
Life Sciences
Lung - diagnostic imaging
lung ultrasound
Lungs
Male
Medical imaging
Middle Aged
Organ Dysfunction Scores
Original
Pandemics
Pleura
Pleura - diagnostic imaging
Pneumonia, Viral - diagnosis
Pneumonia, Viral - diagnostic imaging
Polymerase Chain Reaction
Prediction models
Predictive Value of Tests
RNA-directed DNA polymerase
ROC Curve
Sensitivity and Specificity
Triage
Ultrasonic imaging
Ultrasonography
Ultrasound
title The association of lung ultrasound images with COVID‐19 infection in an emergency room cohort
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