Identification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma

Aberrant methylated genes (DMGs) play an important role in the etiology and pathogenesis of esophageal squamous cell carcinoma (ESCC). In this study, we aimed to integrate three cohorts profile datasets to ascertain aberrant methylated-differentially expressed genes and pathways associated with ESCC...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.9735-9735, Article 9735
Hauptverfasser:	Han, Bao-Ai, Yang, Xiu-Ping, Hosseini, Davood K, Zhang, Po, Zhang, Ya, Yu, Jin-Tao, Chen, Shan, Zhang, Fan, Zhou, Tao, Sun, Hai-Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	119/118 631/67/2324 631/67/68/2486 9/10 AKT protein Bioinformatics Biomarkers, Tumor - genetics Cell cycle Cohort Studies Computational Biology Databases, Genetic DNA methylation DNA Methylation - genetics DNA microarrays Esophageal cancer Esophageal Neoplasms - genetics Esophageal Squamous Cell Carcinoma - genetics Esophageal Squamous Cell Carcinoma - metabolism Esophagus Etiology Gene expression Gene Expression - genetics Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Gene Ontology Gene Regulatory Networks Genomes Humanities and Social Sciences Humans Methylation Microarray Analysis Molecular modelling multidisciplinary Protein interaction Protein Interaction Maps - genetics Science Science (multidisciplinary) Signal transduction Signal Transduction - genetics Software Squamous cell carcinoma Transcriptome - genetics
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