Hesperidin Loaded on Gold Nanoparticles as a Drug Delivery System for a Successful Biocompatible, Anti-Cancer, Anti-Inflammatory and Phagocytosis Inducer Model

Hesperidin is a flavonoid glycoside with proven therapeutic activities for various diseases, including cancer. However, its poor solubility and bioavailability render it only slightly absorbed, requiring a delivery system to reach its therapeutic target. Hesperidin loaded on gold nanoparticles (Hsp-...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.9362, Article 9362
Hauptverfasser:	Sulaiman, Ghassan M., Waheeb, Hanaa M., Jabir, Majid S., Khazaal, Shaymaa H., Dewir, Yaser Hassan, Naidoo, Yougasphree
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154 631/1647 631/61 631/67 Acridine orange Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Apoptosis Ascites Ascites tumor cells Bioavailability Bone marrow Breast cancer Cancer Cell proliferation Cytotoxicity Drug Carriers - chemistry Drug delivery Drug Liberation Ehrlich ascites tumor Ehrlich ascites tumor cells Epithelial cells Flavonoids Gold Gold - chemistry Hesperidin Hesperidin - chemistry Hesperidin - pharmacology Humanities and Social Sciences Humans Inflammation Interleukin 6 Iodides Kidneys Macrophages Male Materials Testing Metal Nanoparticles - chemistry Mice multidisciplinary Nanoparticles Oxidative Stress - drug effects Phagocytosis Phagocytosis - drug effects Science Science (multidisciplinary) Spleen Statistical analysis Tumor cells Ultraviolet spectroscopy Zeta potential
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