Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected
Polymorphic Batesian mimics exhibit multiple protective morphs that each mimic a different noxious model. Here, we study the genomic transitions leading to the evolution of different mimetic wing patterns in the polymorphic Mocker Swallowtail We generated a draft genome (231 Mb over 30 chromosomes)...
Gespeichert in:
| Veröffentlicht in: | Proceedings of the Royal Society. B, Biological sciences Biological sciences, 2020-05, Vol.287 (1926), p.20200443 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1926 |
| container_start_page | 20200443 |
| container_title | Proceedings of the Royal Society. B, Biological sciences |
| container_volume | 287 |
| creator | Timmermans, Martijn J T N Srivathsan, Amrita Collins, Steve Meier, Rudolf Vogler, Alfried P |
| description | Polymorphic Batesian mimics exhibit multiple protective morphs that each mimic a different noxious model. Here, we study the genomic transitions leading to the evolution of different mimetic wing patterns in the polymorphic Mocker Swallowtail
We generated a draft genome (231 Mb over 30 chromosomes) and re-sequenced individuals of three morphs. Genome-wide single nucleotide polymorphism (SNP) analysis revealed elevated linkage disequilibrium and divergence between morphs in the regulatory region of
a developmental gene previously implicated in the mimicry switch
The diverged region exhibits a discrete chromosomal inversion (of 40 kb) relative to the ancestral orientation that is associated with the
morph, but not with the bottom-recessive
morph or with non-mimetic allopatric populations. The functional role of this inversion in the expression of the novel phenotype is currently unknown, but by preventing recombination, it allows the stable inheritance of divergent alleles enabling geographic spread and local coexistence of multiple adaptive morphs. |
| doi_str_mv | 10.1098/rspb.2020.0443 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7282906</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>32345166</sourcerecordid><originalsourceid>FETCH-LOGICAL-c539t-9a92b4b2dd4b0539bf4aec5a787b15f0f854fa8546856613c7073d43ababaf6c3</originalsourceid><addsrcrecordid>eNpVkFtLwzAYhoMobk5vvZT8gdYce7gRZHiCiV7odfiaQxfp2pF2g_17002HEkhCvvd5Aw9C15SklJTFbejXVcoIIykRgp-gKRU5TVgpxSmakjJjSSEkm6CLvv8ihJSykOdowhkXkmbZFA2vfuV12GHjtzb03nkNg-9a7Fv8Dmvf-A4bCAbaTY-3HjDg2rZdZGJiTxyyw9LiYOtNA0MX2-J1HHQO27YO4BtrcLIn9GDNJTpz0PT26uecoc_Hh4_5c7J4e3qZ3y8SLXk5JCWUrBIVM0ZUJL5UToDVEvIir6h0xBVSOIhbVsgso1znJOdGcKjicpnmM3R36F1vqpU12rZDgEatg19B2KkOvPo_af1S1d1W5axgJcliQXoo0KHr-2DdkaVEjf7V6F-N_tXoPwI3f388xn-F82_83oWs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected</title><source>Jstor Complete Legacy</source><source>MEDLINE</source><source>PubMed Central</source><creator>Timmermans, Martijn J T N ; Srivathsan, Amrita ; Collins, Steve ; Meier, Rudolf ; Vogler, Alfried P</creator><creatorcontrib>Timmermans, Martijn J T N ; Srivathsan, Amrita ; Collins, Steve ; Meier, Rudolf ; Vogler, Alfried P</creatorcontrib><description>Polymorphic Batesian mimics exhibit multiple protective morphs that each mimic a different noxious model. Here, we study the genomic transitions leading to the evolution of different mimetic wing patterns in the polymorphic Mocker Swallowtail
We generated a draft genome (231 Mb over 30 chromosomes) and re-sequenced individuals of three morphs. Genome-wide single nucleotide polymorphism (SNP) analysis revealed elevated linkage disequilibrium and divergence between morphs in the regulatory region of
a developmental gene previously implicated in the mimicry switch
The diverged region exhibits a discrete chromosomal inversion (of 40 kb) relative to the ancestral orientation that is associated with the
morph, but not with the bottom-recessive
morph or with non-mimetic allopatric populations. The functional role of this inversion in the expression of the novel phenotype is currently unknown, but by preventing recombination, it allows the stable inheritance of divergent alleles enabling geographic spread and local coexistence of multiple adaptive morphs.</description><identifier>ISSN: 0962-8452</identifier><identifier>EISSN: 1471-2954</identifier><identifier>DOI: 10.1098/rspb.2020.0443</identifier><identifier>PMID: 32345166</identifier><language>eng</language><publisher>England: The Royal Society</publisher><subject>Animals ; Biological Mimicry - physiology ; Butterflies - parasitology ; Chromosome Inversion ; Evolution ; Genes, Insect ; Genomics ; Linkage Disequilibrium ; Phenotype ; Regulatory Sequences, Nucleic Acid ; Wings, Animal</subject><ispartof>Proceedings of the Royal Society. B, Biological sciences, 2020-05, Vol.287 (1926), p.20200443</ispartof><rights>2020 The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c539t-9a92b4b2dd4b0539bf4aec5a787b15f0f854fa8546856613c7073d43ababaf6c3</citedby><cites>FETCH-LOGICAL-c539t-9a92b4b2dd4b0539bf4aec5a787b15f0f854fa8546856613c7073d43ababaf6c3</cites><orcidid>0000-0002-5024-9053 ; 0000-0002-4452-2885</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282906/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282906/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32345166$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Timmermans, Martijn J T N</creatorcontrib><creatorcontrib>Srivathsan, Amrita</creatorcontrib><creatorcontrib>Collins, Steve</creatorcontrib><creatorcontrib>Meier, Rudolf</creatorcontrib><creatorcontrib>Vogler, Alfried P</creatorcontrib><title>Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected</title><title>Proceedings of the Royal Society. B, Biological sciences</title><addtitle>Proc Biol Sci</addtitle><description>Polymorphic Batesian mimics exhibit multiple protective morphs that each mimic a different noxious model. Here, we study the genomic transitions leading to the evolution of different mimetic wing patterns in the polymorphic Mocker Swallowtail
We generated a draft genome (231 Mb over 30 chromosomes) and re-sequenced individuals of three morphs. Genome-wide single nucleotide polymorphism (SNP) analysis revealed elevated linkage disequilibrium and divergence between morphs in the regulatory region of
a developmental gene previously implicated in the mimicry switch
The diverged region exhibits a discrete chromosomal inversion (of 40 kb) relative to the ancestral orientation that is associated with the
morph, but not with the bottom-recessive
morph or with non-mimetic allopatric populations. The functional role of this inversion in the expression of the novel phenotype is currently unknown, but by preventing recombination, it allows the stable inheritance of divergent alleles enabling geographic spread and local coexistence of multiple adaptive morphs.</description><subject>Animals</subject><subject>Biological Mimicry - physiology</subject><subject>Butterflies - parasitology</subject><subject>Chromosome Inversion</subject><subject>Evolution</subject><subject>Genes, Insect</subject><subject>Genomics</subject><subject>Linkage Disequilibrium</subject><subject>Phenotype</subject><subject>Regulatory Sequences, Nucleic Acid</subject><subject>Wings, Animal</subject><issn>0962-8452</issn><issn>1471-2954</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkFtLwzAYhoMobk5vvZT8gdYce7gRZHiCiV7odfiaQxfp2pF2g_17002HEkhCvvd5Aw9C15SklJTFbejXVcoIIykRgp-gKRU5TVgpxSmakjJjSSEkm6CLvv8ihJSykOdowhkXkmbZFA2vfuV12GHjtzb03nkNg-9a7Fv8Dmvf-A4bCAbaTY-3HjDg2rZdZGJiTxyyw9LiYOtNA0MX2-J1HHQO27YO4BtrcLIn9GDNJTpz0PT26uecoc_Hh4_5c7J4e3qZ3y8SLXk5JCWUrBIVM0ZUJL5UToDVEvIir6h0xBVSOIhbVsgso1znJOdGcKjicpnmM3R36F1vqpU12rZDgEatg19B2KkOvPo_af1S1d1W5axgJcliQXoo0KHr-2DdkaVEjf7V6F-N_tXoPwI3f388xn-F82_83oWs</recordid><startdate>20200513</startdate><enddate>20200513</enddate><creator>Timmermans, Martijn J T N</creator><creator>Srivathsan, Amrita</creator><creator>Collins, Steve</creator><creator>Meier, Rudolf</creator><creator>Vogler, Alfried P</creator><general>The Royal Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5024-9053</orcidid><orcidid>https://orcid.org/0000-0002-4452-2885</orcidid></search><sort><creationdate>20200513</creationdate><title>Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected</title><author>Timmermans, Martijn J T N ; Srivathsan, Amrita ; Collins, Steve ; Meier, Rudolf ; Vogler, Alfried P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c539t-9a92b4b2dd4b0539bf4aec5a787b15f0f854fa8546856613c7073d43ababaf6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Biological Mimicry - physiology</topic><topic>Butterflies - parasitology</topic><topic>Chromosome Inversion</topic><topic>Evolution</topic><topic>Genes, Insect</topic><topic>Genomics</topic><topic>Linkage Disequilibrium</topic><topic>Phenotype</topic><topic>Regulatory Sequences, Nucleic Acid</topic><topic>Wings, Animal</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Timmermans, Martijn J T N</creatorcontrib><creatorcontrib>Srivathsan, Amrita</creatorcontrib><creatorcontrib>Collins, Steve</creatorcontrib><creatorcontrib>Meier, Rudolf</creatorcontrib><creatorcontrib>Vogler, Alfried P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Timmermans, Martijn J T N</au><au>Srivathsan, Amrita</au><au>Collins, Steve</au><au>Meier, Rudolf</au><au>Vogler, Alfried P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected</atitle><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle><addtitle>Proc Biol Sci</addtitle><date>2020-05-13</date><risdate>2020</risdate><volume>287</volume><issue>1926</issue><spage>20200443</spage><pages>20200443-</pages><issn>0962-8452</issn><eissn>1471-2954</eissn><abstract>Polymorphic Batesian mimics exhibit multiple protective morphs that each mimic a different noxious model. Here, we study the genomic transitions leading to the evolution of different mimetic wing patterns in the polymorphic Mocker Swallowtail
We generated a draft genome (231 Mb over 30 chromosomes) and re-sequenced individuals of three morphs. Genome-wide single nucleotide polymorphism (SNP) analysis revealed elevated linkage disequilibrium and divergence between morphs in the regulatory region of
a developmental gene previously implicated in the mimicry switch
The diverged region exhibits a discrete chromosomal inversion (of 40 kb) relative to the ancestral orientation that is associated with the
morph, but not with the bottom-recessive
morph or with non-mimetic allopatric populations. The functional role of this inversion in the expression of the novel phenotype is currently unknown, but by preventing recombination, it allows the stable inheritance of divergent alleles enabling geographic spread and local coexistence of multiple adaptive morphs.</abstract><cop>England</cop><pub>The Royal Society</pub><pmid>32345166</pmid><doi>10.1098/rspb.2020.0443</doi><orcidid>https://orcid.org/0000-0002-5024-9053</orcidid><orcidid>https://orcid.org/0000-0002-4452-2885</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0962-8452 |
| ispartof | Proceedings of the Royal Society. B, Biological sciences, 2020-05, Vol.287 (1926), p.20200443 |
| issn | 0962-8452 1471-2954 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7282906 |
| source | Jstor Complete Legacy; MEDLINE; PubMed Central |
| subjects | Animals Biological Mimicry - physiology Butterflies - parasitology Chromosome Inversion Evolution Genes, Insect Genomics Linkage Disequilibrium Phenotype Regulatory Sequences, Nucleic Acid Wings, Animal |
| title | Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed - invected |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T02%3A43%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mimicry%20diversification%20in%20Papilio%20dardanus%20via%20a%20genomic%20inversion%20in%20the%20regulatory%20region%20of%20engrailed%20-%20invected&rft.jtitle=Proceedings%20of%20the%20Royal%20Society.%20B,%20Biological%20sciences&rft.au=Timmermans,%20Martijn%20J%20T%20N&rft.date=2020-05-13&rft.volume=287&rft.issue=1926&rft.spage=20200443&rft.pages=20200443-&rft.issn=0962-8452&rft.eissn=1471-2954&rft_id=info:doi/10.1098/rspb.2020.0443&rft_dat=%3Cpubmed_cross%3E32345166%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/32345166&rfr_iscdi=true |