Effects of Compound Centella on Oxidative Stress and Keap1-Nrf2-ARE Pathway Expression in Diabetic Kidney Disease Rats

The formula of Compound Centella mainly contains 3 traditional Chinese herbs: Centella asiatica (L.) Urb. (JiXueCao), Astragalus Membranaceus Fish. (HuangQi), and Tripterygium wilfordii Hook. f. (LeiGongTeng). Though this formula is effective for treating diabetic kidney disease (DKD) in clinic, the...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-13
Hauptverfasser:	Chen, Hongyu, Miao, Jianxia, Chen, Xueming, Li, Jian, Zeng, Jiali, Zhu, Qin, Jin, Qinyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal experimentation Antibodies Antioxidants Biological products Centella Chinese medicine Chromatography Creatinine Diabetes Diabetes mellitus Diabetic nephropathy Drug dosages Experiments Feeds Glucose Heme Herbal medicine Herbs High performance liquid chromatography Immunohistochemistry Kidney diseases Laboratory animals Malondialdehyde Medicine, Botanic Medicine, Herbal mRNA Nitrogen Oxidases Oxidative stress Pharmaceuticals Phenols Physiological aspects Potassium Streptozocin Transmission electron microscopy Triptolide
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