Directed evolution of Anabaena variabilis phenylalanine ammonia-lyase (PAL) identifies mutants with enhanced activities
There is broad interest in engineering phenylalanine ammonia-lyase (PAL) for its biocatalytic applications in industry and medicine. While site-specific mutagenesis has been employed to improve PAL stability or substrate specificity, combinatorial techniques are poorly explored. Here, we report deve...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-05, Vol.56 (39), p.5255-5258 |
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Sprache: | eng |
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