Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement
We herein report a 50-year-old woman who suffered from tubulointerstitial nephritis with antimitochondrial M2 antibody, distal renal tubular acidosis, and Fanconi syndrome. Our case also had interstitial pneumonia. After initially successful glucocorticoid therapy, tubulointerstitial nephritis and i...
Gespeichert in:
| Veröffentlicht in: | Internal Medicine 2020/05/01, Vol.59(9), pp.1179-1187 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1187 |
|---|---|
| container_issue | 9 |
| container_start_page | 1179 |
| container_title | Internal Medicine |
| container_volume | 59 |
| creator | Nakamori, Aya Akagaki, Fuyuko Yamaguchi, Yoshito Sugiura, Toshihiro |
| description | We herein report a 50-year-old woman who suffered from tubulointerstitial nephritis with antimitochondrial M2 antibody, distal renal tubular acidosis, and Fanconi syndrome. Our case also had interstitial pneumonia. After initially successful glucocorticoid therapy, tubulointerstitial nephritis and interstitial pneumonia relapsed. After the second successful round of glucocorticoid therapy, tubulointerstitial nephritis relapsed again and responded to glucocorticoid and azathioprine. This case might indicate (1) the association between pulmonary involvement and tubulointerstitial nephritis with antimitochondrial antibodies and (2) the need for a maintenance dose of glucocorticoid and immunosuppressants in tubulointerstitial nephritis with antimitochondrial antibodies. |
| doi_str_mv | 10.2169/internalmedicine.4048-19 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7270750</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2354734354</sourcerecordid><originalsourceid>FETCH-LOGICAL-c609t-70e14e516b5bebacfa1f109339cd0086c9a55284f5f745fd8d4152e3f14cfe313</originalsourceid><addsrcrecordid>eNplkU1v1DAQhiMEokvhL6BIXLik-HMTX5BWFR-VSkGonC3HmWy8cuxgO4v23-N0lxWUy9gaP_POeN6iKDG6Ingt3hmXIDhlR-iMNg6uGGJNhcWTYoUpE1VNKH9arJDATUVyuChexLhDiDa1IM-LC0oQx7Rhq8J9B6umaNy2vJ_b2foH6ZhMMsqWdzANIV9j-cukody4ZEaTvB6868ICfCEPydZ3h3KjtR8n5Qx0ZXsov8129E6FQ3nj9t7uYQSXXhbPemUjvDqdl8WPjx_urz9Xt18_3Vxvbiu9RiJVNQLMgON1y1tole4V7jESlArdIdSstVCck4b1vK8Z77umY5gToD1mugeK6WXx_qg7zW1eks6tg7JyCmbME0mvjPz3xZlBbv1e1qRGNUdZ4O1JIPifM8QkRxM1WKsc-DnKvGBWU5ZjRt88Qnd-XtxZKFETljVFppojpYOPMUB_HgYjuZgqH5sqF1MlXkpf__2Zc-EfFzNwdwR2MaktnAEVktEW_lfmQoolnDqcQT2oIMHR3ybuw7k</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2397247279</pqid></control><display><type>article</type><title>Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement</title><source>J-STAGE Free</source><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Nakamori, Aya ; Akagaki, Fuyuko ; Yamaguchi, Yoshito ; Sugiura, Toshihiro</creator><creatorcontrib>Nakamori, Aya ; Akagaki, Fuyuko ; Yamaguchi, Yoshito ; Sugiura, Toshihiro</creatorcontrib><description>We herein report a 50-year-old woman who suffered from tubulointerstitial nephritis with antimitochondrial M2 antibody, distal renal tubular acidosis, and Fanconi syndrome. Our case also had interstitial pneumonia. After initially successful glucocorticoid therapy, tubulointerstitial nephritis and interstitial pneumonia relapsed. After the second successful round of glucocorticoid therapy, tubulointerstitial nephritis relapsed again and responded to glucocorticoid and azathioprine. This case might indicate (1) the association between pulmonary involvement and tubulointerstitial nephritis with antimitochondrial antibodies and (2) the need for a maintenance dose of glucocorticoid and immunosuppressants in tubulointerstitial nephritis with antimitochondrial antibodies.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.4048-19</identifier><identifier>PMID: 32051384</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Acidosis ; Antibodies ; antimitochondrial antibodies ; Azathioprine ; Case Report ; distal renal tubular acidosis ; Fanconi syndrome ; Glucocorticoids ; Health risk assessment ; immunosuppressant ; Immunosuppressive agents ; Internal medicine ; Nephritis ; Pneumonia ; pulmonary involvement ; Renal tubular acidosis ; tubulointerstitial nephritis</subject><ispartof>Internal Medicine, 2020/05/01, Vol.59(9), pp.1179-1187</ispartof><rights>2020 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2020</rights><rights>Copyright © 2020 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c609t-70e14e516b5bebacfa1f109339cd0086c9a55284f5f745fd8d4152e3f14cfe313</citedby><cites>FETCH-LOGICAL-c609t-70e14e516b5bebacfa1f109339cd0086c9a55284f5f745fd8d4152e3f14cfe313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270750/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270750/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,1882,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32051384$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakamori, Aya</creatorcontrib><creatorcontrib>Akagaki, Fuyuko</creatorcontrib><creatorcontrib>Yamaguchi, Yoshito</creatorcontrib><creatorcontrib>Sugiura, Toshihiro</creatorcontrib><title>Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>We herein report a 50-year-old woman who suffered from tubulointerstitial nephritis with antimitochondrial M2 antibody, distal renal tubular acidosis, and Fanconi syndrome. Our case also had interstitial pneumonia. After initially successful glucocorticoid therapy, tubulointerstitial nephritis and interstitial pneumonia relapsed. After the second successful round of glucocorticoid therapy, tubulointerstitial nephritis relapsed again and responded to glucocorticoid and azathioprine. This case might indicate (1) the association between pulmonary involvement and tubulointerstitial nephritis with antimitochondrial antibodies and (2) the need for a maintenance dose of glucocorticoid and immunosuppressants in tubulointerstitial nephritis with antimitochondrial antibodies.</description><subject>Acidosis</subject><subject>Antibodies</subject><subject>antimitochondrial antibodies</subject><subject>Azathioprine</subject><subject>Case Report</subject><subject>distal renal tubular acidosis</subject><subject>Fanconi syndrome</subject><subject>Glucocorticoids</subject><subject>Health risk assessment</subject><subject>immunosuppressant</subject><subject>Immunosuppressive agents</subject><subject>Internal medicine</subject><subject>Nephritis</subject><subject>Pneumonia</subject><subject>pulmonary involvement</subject><subject>Renal tubular acidosis</subject><subject>tubulointerstitial nephritis</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNplkU1v1DAQhiMEokvhL6BIXLik-HMTX5BWFR-VSkGonC3HmWy8cuxgO4v23-N0lxWUy9gaP_POeN6iKDG6Ingt3hmXIDhlR-iMNg6uGGJNhcWTYoUpE1VNKH9arJDATUVyuChexLhDiDa1IM-LC0oQx7Rhq8J9B6umaNy2vJ_b2foH6ZhMMsqWdzANIV9j-cukody4ZEaTvB6868ICfCEPydZ3h3KjtR8n5Qx0ZXsov8129E6FQ3nj9t7uYQSXXhbPemUjvDqdl8WPjx_urz9Xt18_3Vxvbiu9RiJVNQLMgON1y1tole4V7jESlArdIdSstVCck4b1vK8Z77umY5gToD1mugeK6WXx_qg7zW1eks6tg7JyCmbME0mvjPz3xZlBbv1e1qRGNUdZ4O1JIPifM8QkRxM1WKsc-DnKvGBWU5ZjRt88Qnd-XtxZKFETljVFppojpYOPMUB_HgYjuZgqH5sqF1MlXkpf__2Zc-EfFzNwdwR2MaktnAEVktEW_lfmQoolnDqcQT2oIMHR3ybuw7k</recordid><startdate>20200501</startdate><enddate>20200501</enddate><creator>Nakamori, Aya</creator><creator>Akagaki, Fuyuko</creator><creator>Yamaguchi, Yoshito</creator><creator>Sugiura, Toshihiro</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200501</creationdate><title>Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement</title><author>Nakamori, Aya ; Akagaki, Fuyuko ; Yamaguchi, Yoshito ; Sugiura, Toshihiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c609t-70e14e516b5bebacfa1f109339cd0086c9a55284f5f745fd8d4152e3f14cfe313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acidosis</topic><topic>Antibodies</topic><topic>antimitochondrial antibodies</topic><topic>Azathioprine</topic><topic>Case Report</topic><topic>distal renal tubular acidosis</topic><topic>Fanconi syndrome</topic><topic>Glucocorticoids</topic><topic>Health risk assessment</topic><topic>immunosuppressant</topic><topic>Immunosuppressive agents</topic><topic>Internal medicine</topic><topic>Nephritis</topic><topic>Pneumonia</topic><topic>pulmonary involvement</topic><topic>Renal tubular acidosis</topic><topic>tubulointerstitial nephritis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakamori, Aya</creatorcontrib><creatorcontrib>Akagaki, Fuyuko</creatorcontrib><creatorcontrib>Yamaguchi, Yoshito</creatorcontrib><creatorcontrib>Sugiura, Toshihiro</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamori, Aya</au><au>Akagaki, Fuyuko</au><au>Yamaguchi, Yoshito</au><au>Sugiura, Toshihiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2020-05-01</date><risdate>2020</risdate><volume>59</volume><issue>9</issue><spage>1179</spage><epage>1187</epage><pages>1179-1187</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We herein report a 50-year-old woman who suffered from tubulointerstitial nephritis with antimitochondrial M2 antibody, distal renal tubular acidosis, and Fanconi syndrome. Our case also had interstitial pneumonia. After initially successful glucocorticoid therapy, tubulointerstitial nephritis and interstitial pneumonia relapsed. After the second successful round of glucocorticoid therapy, tubulointerstitial nephritis relapsed again and responded to glucocorticoid and azathioprine. This case might indicate (1) the association between pulmonary involvement and tubulointerstitial nephritis with antimitochondrial antibodies and (2) the need for a maintenance dose of glucocorticoid and immunosuppressants in tubulointerstitial nephritis with antimitochondrial antibodies.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>32051384</pmid><doi>10.2169/internalmedicine.4048-19</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2020/05/01, Vol.59(9), pp.1179-1187 |
| issn | 0918-2918 1349-7235 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7270750 |
| source | J-STAGE Free; PubMed Central Open Access; PubMed Central |
| subjects | Acidosis Antibodies antimitochondrial antibodies Azathioprine Case Report distal renal tubular acidosis Fanconi syndrome Glucocorticoids Health risk assessment immunosuppressant Immunosuppressive agents Internal medicine Nephritis Pneumonia pulmonary involvement Renal tubular acidosis tubulointerstitial nephritis |
| title | Relapsing Tubulointerstitial Nephritis with Antimitochondrial M2 Antibody Accompanied by Pulmonary Involvement |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T11%3A39%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relapsing%20Tubulointerstitial%20Nephritis%20with%20Antimitochondrial%20M2%20Antibody%20Accompanied%20by%20Pulmonary%20Involvement&rft.jtitle=Internal%20Medicine&rft.au=Nakamori,%20Aya&rft.date=2020-05-01&rft.volume=59&rft.issue=9&rft.spage=1179&rft.epage=1187&rft.pages=1179-1187&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.4048-19&rft_dat=%3Cproquest_pubme%3E2354734354%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2397247279&rft_id=info:pmid/32051384&rfr_iscdi=true |