Nonclinical Pharmacokinetics, Protein Binding, and Elimination of KBP-7072, an Aminomethylcycline Antibiotic, in Animal Models

KBP-7072 is a semisynthetic aminomethylcycline with broad-spectrum activity against Gram-positive and Gram-negative pathogens, including multidrug-resistant bacterial strains. The pharmacokinetics (PK) of KBP-7072 after oral and intravenous (i.v.) administrations of single and multiple doses were in...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2020-05, Vol.64 (6)
Hauptverfasser:	Tan, Xiaojuan, Zhang, Min, Liu, Qingmei, Wang, Ping, Zhou, Tian, Zhu, Yuanju, Chen, Bin, Wang, Meng, Xia, Yong, Benn, Vincent, Yang, Fred, Zhang, Jay
Format:	Artikel
Sprache:	eng
Schlagworte:	Pharmacology
Online-Zugang:	Volltext
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