Significant Efficacy of a Single Low Dose of Primaquine Compared to Stand-Alone Artemisinin Combination Therapy in Reducing Gametocyte Carriage in Cambodian Patients with Uncomplicated Multidrug-Resistant Plasmodium falciparum Malaria

Since 2012, a single low dose of primaquine (SLDPQ; 0.25 mg/kg of body weight) with artemisinin-based combination therapies has been recommended as the first-line treatment of acute uncomplicated malaria to interrupt its transmission, especially in low-transmission settings of multidrug resistance,...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2020-05, Vol.64 (6)
Hauptverfasser:	Vantaux, Amélie, Kim, Saorin, Piv, Eakpor, Chy, Sophy, Berne, Laura, Khim, Nimol, Lek, Dysoley, Siv, Sovannaroth, Mukaka, Mavuto, Taylor, Walter R, Ménard, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Epidemiology and Surveillance Human health and pathology Infectious diseases Life Sciences Pharmaceutical sciences Pharmacology
Online-Zugang:	Volltext
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