Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

IMPORTANCE: Antibiotic overuse drives antibiotic resistance. Gram-negative bacteremia is a common infection that results in substantial antibiotic use. OBJECTIVE: To compare the clinical effectiveness of C-reactive protein (CRP)–guided, 7-day, and 14-day antibiotic durations 30, 60, and 90 days afte...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	JAMA : the journal of the American Medical Association 2020-06, Vol.323 (21), p.2160-2169
Hauptverfasser:	von Dach, Elodie, Albrich, Werner C, Brunel, Anne-Sophie, Prendki, Virginie, Cuvelier, Clémence, Flury, Domenica, Gayet-Ageron, Angèle, Huttner, Benedikt, Kohler, Philipp, Lemmenmeier, Eva, McCallin, Shawna, Rossel, Anne, Harbarth, Stephan, Kaiser, Laurent, Bochud, Pierre-Yves, Huttner, Angela
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Antibiotic resistance Antibiotics Bacteremia Bacteria Blood culture C-reactive protein Clinical trials Failure rates Gram-negative bacteria Health services Immunosuppression Infections Original Investigation Patients Physicians Proteins Restarting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!