NIHBA: a network interdiction approach for metabolic engineering design

Abstract Motivation Flux balance analysis (FBA) based bilevel optimization has been a great success in redesigning metabolic networks for biochemical overproduction. To date, many computational approaches have been developed to solve the resulting bilevel optimization problems. However, most of them...

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Veröffentlicht in:	Bioinformatics 2020-06, Vol.36 (11), p.3482-3492
Hauptverfasser:	Jiang, Shouyong, Wang, Yong, Kaiser, Marcus, Krasnogor, Natalio
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Papers
Online-Zugang:	Volltext
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