Cystic fibrosis transmembrane conductance regulator function, not TAS2R38 gene haplotypes, predict sinus surgery in children and young adults with cystic fibrosis

Background Chronic rhinosinusitis symptomatology begins in early childhood individuals with cystic fibrosis (CF). Cystic fibrosis transmembrane conductance regulator (CFTR) function contributes to sinus development and disease. Genetic variants of the bitter taste receptor TAS2R38 have been suggeste...

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Veröffentlicht in:	International forum of allergy & rhinology 2020-06, Vol.10 (6), p.748-754
Hauptverfasser:	Dalesio, Nicholas M., Aksit, Melis A., Ahn, Kwangmi, Raraigh, Karen S., Collaco, Joseph M., McGrath‐Morrow, Sharon, Zeitlin, Pamela L., An, Steven S., Cutting, Garry R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bitter taste bitter taste receptor CFTR function Children Chloride conductance Cystic fibrosis Genetic diversity Genotyping Haplotypes Rhinosinusitis Sinuses sinusitis Statistical analysis Surgery TAS2R38 Taste receptors Young adults
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