Targeted metabolomic analysis of serum amino acids in the adult Fontan patient with a dominant left ventricle

Growing interest lies in the assessment of the metabolic status of patients with a univentricular circulation after Fontan operation, especially in changes of amino acid metabolism. Using targeted metabolomic examinations, we investigated amino acid metabolism in a homogeneous adult Fontan-patient g...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.8930-8930, Article 8930
Hauptverfasser:	Michel, Miriam, Dubowy, Karl-Otto, Entenmann, Andreas, Karall, Daniela, Adam, Mark Gordian, Zlamy, Manuela, Odri Komazec, Irena, Geiger, Ralf, Niederwanger, Christian, Salvador, Christina, Müller, Udo, Laser, Kai Thorsten, Scholl-Bürgi, Sabine
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308 692/4019/592/75/1539 82 82/58 Amino acid sequence Amino acids Amino Acids - blood Amino Acids - metabolism Asparagine Case-Control Studies Congestive heart failure Coronary Circulation - physiology Energy metabolism Female Fontan Procedure - adverse effects Glutamic acid Heart Defects, Congenital - blood Heart Defects, Congenital - metabolism Heart Defects, Congenital - surgery Heart surgery Histidine Humanities and Social Sciences Humans Hydroxyproline Male Metabolism Metabolomics Methionine multidisciplinary Oxidative metabolism Oxidative Stress Oxygen uptake Pathophysiology Patients Science Science (multidisciplinary) Taurine Threonine Ventricle Ventricular Dysfunction, Left - blood Ventricular Dysfunction, Left - metabolism Young Adult
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