Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T‐cell differentiation along the maternal‐placental circulation

Objectives During human pregnancy, the endothelial cells of the uterine spiral arteries (SPA) are extensively replaced by a subtype of placental trophoblasts, endovascular extravillous trophoblasts (enEVTs), thus establishing a placental‐maternal circulation. On this pathway, foetus‐derived placenta...

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Veröffentlicht in:	Cell proliferation 2020-05, Vol.53 (5), p.e12802-n/a
Hauptverfasser:	Ma, Yeling, Yang, Qian, Fan, Mengjie, Zhang, Lanmei, Gu, Yan, Jia, Wentong, Li, Zhilang, Wang, Feiyang, Li, Yu‐xia, Wang, Jian, Li, Rong, Shao, Xuan, Wang, Yan‐Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Arteries Cardiovascular system CD4 antigen Cell differentiation Circulation Decidua Differentiation (biology) Endothelial cells enEVTs Enzyme-linked immunosorbent assay Fetuses Flow cytometry Foxp3 protein Hospitals Hybridization Immunofluorescence Immunological tolerance Immunoregulation Lymphocytes Lymphocytes T Miscarriage Original Pathogenesis Placenta placental‐maternal circulation Pregnancy RSA TGF‐β1 Transforming growth factor-b1 Tregs Trophoblasts Uterus Zoology
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