Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial

Apathy is a frequent neuropsychiatric symptom in dementia of Alzheimer type and negatively affects the disease course and patients' and caregivers' quality of life. Effective treatment options are needed. To examine the efficacy and safety of the dopamine and noradrenaline reuptake inhibit...

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Veröffentlicht in:	JAMA network open 2020-05, Vol.3 (5), p.e206027
Hauptverfasser:	Maier, Franziska, Spottke, Annika, Bach, Jan-Philipp, Bartels, Claudia, Buerger, Katharina, Dodel, Richard, Fellgiebel, Andreas, Fliessbach, Klaus, Frölich, Lutz, Hausner, Lucrezia, Hellmich, Martin, Klöppel, Stefan, Klostermann, Arne, Kornhuber, Johannes, Laske, Christoph, Peters, Oliver, Priller, Josef, Richter-Schmidinger, Tanja, Schneider, Anja, Shah-Hosseini, Kija, Teipel, Stefan, von Arnim, Christine A F, Wiltfang, Jens, Jessen, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Aged Alzheimer Disease - drug therapy Alzheimer Disease - psychology Antidepressive Agents, Second-Generation - adverse effects Antidepressive Agents, Second-Generation - therapeutic use Apathy Apathy - drug effects Bupropion - adverse effects Bupropion - therapeutic use Clinical trials Dementia Double-Blind Method Female Humans Male Mental Status and Dementia Tests Online Only Original Investigation Psychiatry Quality of life
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