MiR-30e-5p inhibits the migration and invasion of nasopharyngeal carcinoma via regulating the expression of MTA1

The study explored the effect of miR-30e-5p on nasopharyngeal carcinoma (NPC). MiR-30e-5p levels in NPC cancer and adjacent normal samples, in metastatic and non-metastatic cancer samples of NPC, and in NP69 cell and five NPC cell lines were determined by quantitative real-time polymerase chain reac...

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Veröffentlicht in:	Bioscience reports 2020-05, Vol.40 (5)
Hauptverfasser:	Hu, Weiqun, Yao, Wenfeng, Li, Haolin, Chen, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cancer Cell Line, Tumor Cell Migration, Adhesion & Morphology Cell Movement Female Gene Expression Regulation, Neoplastic Humans Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 3 - metabolism MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - metabolism Nasopharyngeal Carcinoma - mortality Nasopharyngeal Carcinoma - secondary Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - mortality Nasopharyngeal Neoplasms - pathology Neoplasm Invasiveness Repressor Proteins - genetics Repressor Proteins - metabolism RNA Signal Transduction Snail Family Transcription Factors - metabolism Trans-Activators - genetics Trans-Activators - metabolism Vimentin - metabolism
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