Comparison of the pharmacological profiles of arginine vasopressin and oxytocin analogs at marmoset, macaque, and human vasopressin 1a receptor

[Display omitted] Arginine vasopressin (AVP) and oxytocin (OT) are nonapeptides that bind to G-protein coupled receptors and influence social behaviors. Consensus mammalian AVP and OT (Leu8-OT) sequences are highly conserved. In marmosets, an amino acid change in the 8th position of the peptide (Pro...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2020-06, Vol.126, p.110060-110060, Article 110060
Hauptverfasser:	Pierce, Marsha L., French, Jeffrey A., Murray, Thomas F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine vasopressin Arginine Vasopressin - analogs & derivatives Arginine Vasopressin - pharmacology Calcium - metabolism Calcium-activated potassium channels Callithrix CHO Cells Cricetulus g-protein coupled receptor Humans Ligands Macaca Oxytocin Oxytocin - analogs & derivatives Oxytocin - pharmacology Potassium Channels, Calcium-Activated - metabolism Receptors, G-Protein-Coupled - metabolism Receptors, Oxytocin - genetics Receptors, Oxytocin - metabolism Receptors, Vasopressin - genetics Receptors, Vasopressin - metabolism Social Behavior Species Specificity Vasopressin receptor 1a
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