Pharmacokinetics in children with chronic kidney disease

In children, the main causes of chronic kidney disease (CKD) are congenital diseases and glomerular disorders. CKD is associated with multiple physiological changes and may therefore influence various pharmacokinetic (PK) parameters. A well-known consequence of CKD on pharmacokinetics is a reduction...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2020-07, Vol.35 (7), p.1153-1172
Hauptverfasser:	Schijvens, Anne M., de Wildt, Saskia N., Schreuder, Michiel F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Child Children Chronic kidney failure Complications and side effects Dose-Response Relationship, Drug Drug dosages Drug therapy Glomerular filtration rate Glomerular Filtration Rate - drug effects Humans Kidney diseases Liver - metabolism Medicine Medicine & Public Health Nephrology Pediatric research Pediatrics Pharmacokinetics Rats Renal function Renal Insufficiency, Chronic - physiopathology Review Toxicity Urology What’s New in Chronic Kidney Disease
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