A quantitative and qualitative analysis of the COVID–19 pandemic model

Global efforts around the world are focused on to discuss several health care strategies for minimizing the impact of the new coronavirus (COVID-19) on the community. As it is clear that this virus becomes a public health threat and spreading easily among individuals. Mathematical models with comput...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chaos, solitons and fractals solitons and fractals, 2020-09, Vol.138, p.109932-109932, Article 109932
Hauptverfasser: Khoshnaw, Sarbaz H.A., Shahzad, Muhammad, Ali, Mehboob, Sultan, Faisal
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 109932
container_issue
container_start_page 109932
container_title Chaos, solitons and fractals
container_volume 138
creator Khoshnaw, Sarbaz H.A.
Shahzad, Muhammad
Ali, Mehboob
Sultan, Faisal
description Global efforts around the world are focused on to discuss several health care strategies for minimizing the impact of the new coronavirus (COVID-19) on the community. As it is clear that this virus becomes a public health threat and spreading easily among individuals. Mathematical models with computational simulations are effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of differential equations with transmission parameters. Some key computational simulations and sensitivity analysis are investigated. Also, the local sensitivities for each model state concerning the model parameters are computed using three different techniques: non-normalizations, half normalizations, and full normalizations. Results based on the computational simulations show that the model dynamics are significantly changed for different key model parameters. Interestingly, we identify that transition rates between asymptomatic infected with both reported and unreported symptomatic infected individuals are very sensitive parameters concerning model variables in spreading this disease. This helps international efforts to reduce the number of infected individuals from the disease and to prevent the propagation of new coronavirus more widely on the community. Another novelty of this paper is the identification of the critical model parameters, which makes it easy to be used by biologists with less knowledge of mathematical modeling and also facilitates the improvement of the model for future development theoretically and practically.
doi_str_mv 10.1016/j.chaos.2020.109932
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7247488</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0960077920303313</els_id><sourcerecordid>2412213705</sourcerecordid><originalsourceid>FETCH-LOGICAL-c436t-b59ad5da124ca80a9c4451f1321ba5e7f3b446769591910020fd2928939c2f593</originalsourceid><addsrcrecordid>eNp9UctOwzAQtBCIlscXcMmRS4pfieMDSFV5tFKlXoCr5Tgb6iqJ2zit1Bv_wB_yJSSkAnHhsFrt7sysdgehK4JHBJP4ZjUyS-38iGLadaRk9AgNSSJYSJNEHKMhljEOsRBygM68X2GMCY7pKRowGtE2xBBNx8Fmq6vGNrqxOwh0lXWN4rfWxd5bH7g8aJYQTBavs_vP9w8ig3WLhdKaoHQZFBfoJNeFh8tDPkcvjw_Pk2k4XzzNJuN5aDiLmzCNpM6iTBPKjU6wlobziOSEUZLqCETOUs5jEctIEklwe1qeUUkTyaSheSTZObrrddfbtITMQNXUulDr2pa63iunrfo7qexSvbmdEpQLniStwPVBoHabLfhGldYbKApdgdt6RTmhlDCBoxbKeqipnfc15D9rCFadB2qlvj1QnQeq96Bl3fYsaN-ws1ArbyxUBjJbg2lU5uy__C_13o8f</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2412213705</pqid></control><display><type>article</type><title>A quantitative and qualitative analysis of the COVID–19 pandemic model</title><source>Elsevier ScienceDirect Journals Complete</source><creator>Khoshnaw, Sarbaz H.A. ; Shahzad, Muhammad ; Ali, Mehboob ; Sultan, Faisal</creator><creatorcontrib>Khoshnaw, Sarbaz H.A. ; Shahzad, Muhammad ; Ali, Mehboob ; Sultan, Faisal</creatorcontrib><description>Global efforts around the world are focused on to discuss several health care strategies for minimizing the impact of the new coronavirus (COVID-19) on the community. As it is clear that this virus becomes a public health threat and spreading easily among individuals. Mathematical models with computational simulations are effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of differential equations with transmission parameters. Some key computational simulations and sensitivity analysis are investigated. Also, the local sensitivities for each model state concerning the model parameters are computed using three different techniques: non-normalizations, half normalizations, and full normalizations. Results based on the computational simulations show that the model dynamics are significantly changed for different key model parameters. Interestingly, we identify that transition rates between asymptomatic infected with both reported and unreported symptomatic infected individuals are very sensitive parameters concerning model variables in spreading this disease. This helps international efforts to reduce the number of infected individuals from the disease and to prevent the propagation of new coronavirus more widely on the community. Another novelty of this paper is the identification of the critical model parameters, which makes it easy to be used by biologists with less knowledge of mathematical modeling and also facilitates the improvement of the model for future development theoretically and practically.</description><identifier>ISSN: 0960-0779</identifier><identifier>EISSN: 1873-2887</identifier><identifier>EISSN: 0960-0779</identifier><identifier>DOI: 10.1016/j.chaos.2020.109932</identifier><identifier>PMID: 32523257</identifier><language>eng</language><publisher>Elsevier Ltd</publisher><subject>Computational simulations ; Coronavirus disease (COVID-19) ; Mathematical modeling ; Model reduction ; Sensitivity analysis</subject><ispartof>Chaos, solitons and fractals, 2020-09, Vol.138, p.109932-109932, Article 109932</ispartof><rights>2020</rights><rights>2020 Elsevier Ltd. All rights reserved. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-b59ad5da124ca80a9c4451f1321ba5e7f3b446769591910020fd2928939c2f593</citedby><cites>FETCH-LOGICAL-c436t-b59ad5da124ca80a9c4451f1321ba5e7f3b446769591910020fd2928939c2f593</cites><orcidid>0000-0002-2290-804X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chaos.2020.109932$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995</link.rule.ids></links><search><creatorcontrib>Khoshnaw, Sarbaz H.A.</creatorcontrib><creatorcontrib>Shahzad, Muhammad</creatorcontrib><creatorcontrib>Ali, Mehboob</creatorcontrib><creatorcontrib>Sultan, Faisal</creatorcontrib><title>A quantitative and qualitative analysis of the COVID–19 pandemic model</title><title>Chaos, solitons and fractals</title><description>Global efforts around the world are focused on to discuss several health care strategies for minimizing the impact of the new coronavirus (COVID-19) on the community. As it is clear that this virus becomes a public health threat and spreading easily among individuals. Mathematical models with computational simulations are effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of differential equations with transmission parameters. Some key computational simulations and sensitivity analysis are investigated. Also, the local sensitivities for each model state concerning the model parameters are computed using three different techniques: non-normalizations, half normalizations, and full normalizations. Results based on the computational simulations show that the model dynamics are significantly changed for different key model parameters. Interestingly, we identify that transition rates between asymptomatic infected with both reported and unreported symptomatic infected individuals are very sensitive parameters concerning model variables in spreading this disease. This helps international efforts to reduce the number of infected individuals from the disease and to prevent the propagation of new coronavirus more widely on the community. Another novelty of this paper is the identification of the critical model parameters, which makes it easy to be used by biologists with less knowledge of mathematical modeling and also facilitates the improvement of the model for future development theoretically and practically.</description><subject>Computational simulations</subject><subject>Coronavirus disease (COVID-19)</subject><subject>Mathematical modeling</subject><subject>Model reduction</subject><subject>Sensitivity analysis</subject><issn>0960-0779</issn><issn>1873-2887</issn><issn>0960-0779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9UctOwzAQtBCIlscXcMmRS4pfieMDSFV5tFKlXoCr5Tgb6iqJ2zit1Bv_wB_yJSSkAnHhsFrt7sysdgehK4JHBJP4ZjUyS-38iGLadaRk9AgNSSJYSJNEHKMhljEOsRBygM68X2GMCY7pKRowGtE2xBBNx8Fmq6vGNrqxOwh0lXWN4rfWxd5bH7g8aJYQTBavs_vP9w8ig3WLhdKaoHQZFBfoJNeFh8tDPkcvjw_Pk2k4XzzNJuN5aDiLmzCNpM6iTBPKjU6wlobziOSEUZLqCETOUs5jEctIEklwe1qeUUkTyaSheSTZObrrddfbtITMQNXUulDr2pa63iunrfo7qexSvbmdEpQLniStwPVBoHabLfhGldYbKApdgdt6RTmhlDCBoxbKeqipnfc15D9rCFadB2qlvj1QnQeq96Bl3fYsaN-ws1ArbyxUBjJbg2lU5uy__C_13o8f</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Khoshnaw, Sarbaz H.A.</creator><creator>Shahzad, Muhammad</creator><creator>Ali, Mehboob</creator><creator>Sultan, Faisal</creator><general>Elsevier Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2290-804X</orcidid></search><sort><creationdate>20200901</creationdate><title>A quantitative and qualitative analysis of the COVID–19 pandemic model</title><author>Khoshnaw, Sarbaz H.A. ; Shahzad, Muhammad ; Ali, Mehboob ; Sultan, Faisal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-b59ad5da124ca80a9c4451f1321ba5e7f3b446769591910020fd2928939c2f593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Computational simulations</topic><topic>Coronavirus disease (COVID-19)</topic><topic>Mathematical modeling</topic><topic>Model reduction</topic><topic>Sensitivity analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khoshnaw, Sarbaz H.A.</creatorcontrib><creatorcontrib>Shahzad, Muhammad</creatorcontrib><creatorcontrib>Ali, Mehboob</creatorcontrib><creatorcontrib>Sultan, Faisal</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chaos, solitons and fractals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khoshnaw, Sarbaz H.A.</au><au>Shahzad, Muhammad</au><au>Ali, Mehboob</au><au>Sultan, Faisal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A quantitative and qualitative analysis of the COVID–19 pandemic model</atitle><jtitle>Chaos, solitons and fractals</jtitle><date>2020-09-01</date><risdate>2020</risdate><volume>138</volume><spage>109932</spage><epage>109932</epage><pages>109932-109932</pages><artnum>109932</artnum><issn>0960-0779</issn><eissn>1873-2887</eissn><eissn>0960-0779</eissn><abstract>Global efforts around the world are focused on to discuss several health care strategies for minimizing the impact of the new coronavirus (COVID-19) on the community. As it is clear that this virus becomes a public health threat and spreading easily among individuals. Mathematical models with computational simulations are effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of differential equations with transmission parameters. Some key computational simulations and sensitivity analysis are investigated. Also, the local sensitivities for each model state concerning the model parameters are computed using three different techniques: non-normalizations, half normalizations, and full normalizations. Results based on the computational simulations show that the model dynamics are significantly changed for different key model parameters. Interestingly, we identify that transition rates between asymptomatic infected with both reported and unreported symptomatic infected individuals are very sensitive parameters concerning model variables in spreading this disease. This helps international efforts to reduce the number of infected individuals from the disease and to prevent the propagation of new coronavirus more widely on the community. Another novelty of this paper is the identification of the critical model parameters, which makes it easy to be used by biologists with less knowledge of mathematical modeling and also facilitates the improvement of the model for future development theoretically and practically.</abstract><pub>Elsevier Ltd</pub><pmid>32523257</pmid><doi>10.1016/j.chaos.2020.109932</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-2290-804X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0960-0779
ispartof Chaos, solitons and fractals, 2020-09, Vol.138, p.109932-109932, Article 109932
issn 0960-0779
1873-2887
0960-0779
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7247488
source Elsevier ScienceDirect Journals Complete
subjects Computational simulations
Coronavirus disease (COVID-19)
Mathematical modeling
Model reduction
Sensitivity analysis
title A quantitative and qualitative analysis of the COVID–19 pandemic model
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T09%3A39%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20quantitative%20and%20qualitative%20analysis%20of%20the%20COVID%E2%80%9319%20pandemic%20model&rft.jtitle=Chaos,%20solitons%20and%20fractals&rft.au=Khoshnaw,%20Sarbaz%20H.A.&rft.date=2020-09-01&rft.volume=138&rft.spage=109932&rft.epage=109932&rft.pages=109932-109932&rft.artnum=109932&rft.issn=0960-0779&rft.eissn=1873-2887&rft_id=info:doi/10.1016/j.chaos.2020.109932&rft_dat=%3Cproquest_pubme%3E2412213705%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2412213705&rft_id=info:pmid/32523257&rft_els_id=S0960077920303313&rfr_iscdi=true