Modeling Neurodegenerative Disorders in Drosophila melanogaster
provides a powerful genetic model system in which to investigate the molecular mechanisms underlying neurodegenerative diseases. In this review, we discuss recent progress in modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease,...
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| Veröffentlicht in: | International journal of molecular sciences 2020-04, Vol.21 (9), p.3055 |
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| container_issue | 9 |
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| container_title | International journal of molecular sciences |
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| creator | Bolus, Harris Crocker, Kassi Boekhoff-Falk, Grace Chtarbanova, Stanislava |
| description | provides a powerful genetic model system in which to investigate the molecular mechanisms underlying neurodegenerative diseases. In this review, we discuss recent progress in
modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Ataxia Telangiectasia, and neurodegeneration related to mitochondrial dysfunction or traumatic brain injury. We close by discussing recent progress using
models of neural regeneration and how these are likely to provide critical insights into future treatments for neurodegenerative disorders. |
| doi_str_mv | 10.3390/ijms21093055 |
| format | Article |
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modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Ataxia Telangiectasia, and neurodegeneration related to mitochondrial dysfunction or traumatic brain injury. We close by discussing recent progress using
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In this review, we discuss recent progress in
modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Ataxia Telangiectasia, and neurodegeneration related to mitochondrial dysfunction or traumatic brain injury. We close by discussing recent progress using
models of neural regeneration and how these are likely to provide critical insights into future treatments for neurodegenerative disorders.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>32357532</pmid><doi>10.3390/ijms21093055</doi><orcidid>https://orcid.org/0000-0001-7865-028X</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Alzheimer's disease Amyotrophic lateral sclerosis Animals Animals, Genetically Modified Ataxia Ataxia telangiectasia Cell adhesion & migration Copper Dementia Disease Disease Models, Animal Dopamine Drosophila Drosophila melanogaster Drosophila Proteins - genetics Genes Genetic Predisposition to Disease - genetics Humans Huntingtons disease Hypotheses Insects Lifestyles Mitochondria Modelling Molecular modelling Morphology Mutation Nerve Regeneration Nervous system Neurodegeneration Neurodegenerative Diseases - genetics Neurodegenerative Diseases - pathology Parkinson's disease Pathology Peptides Proteins Regeneration Review Studies Traumatic brain injury Zinc |
| title | Modeling Neurodegenerative Disorders in Drosophila melanogaster |
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