Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology

We report the neuropathological findings of a patient who died from complications of COVID-19. The decedent was initially hospitalized for surgical management of underlying coronary artery disease. He developed post-operative complications and was evaluated with chest imaging studies. The chest comp...

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Veröffentlicht in:	Acta neuropathologica 2020-07, Vol.140 (1), p.1-6
Hauptverfasser:	Reichard, R. Ross, Kashani, Kianoush B., Boire, Nicholas A., Constantopoulos, Eleni, Guo, Yong, Lucchinetti, Claudia F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Autopsy B cells Betacoronavirus - pathogenicity Brain - pathology Cardiovascular disease Case Report Central nervous system Cerebral hemispheres Chest Computed tomography Coronary artery Coronary heart disease Coronavirus Infections - diagnosis Coronavirus Infections - pathology Coronavirus Infections - virology Coronaviruses COVID-19 Demyelination Development and progression Encephalomyelitis Health aspects Heart diseases Hemorrhage Humans Lesions Macrophages Magnetic Resonance Imaging - methods Male Medical research Medicine Medicine & Public Health Medicine, Experimental Nervous System Diseases - pathology Neurological complications Neuropathology Neuropathology - methods Neurosciences Pandemics Pathology Patients Pneumonia, Viral - diagnosis Pneumonia, Viral - pathology Pneumonia, Viral - virology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Substantia alba Tomography, X-Ray Computed - methods
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