Prohibitin levels regulate OMA1 activity and turnover in neurons

The GTPase OPA1 and the AAA-protease OMA1 serve well-established roles in mitochondrial stress responses and mitochondria-initiated cell death. In addition to its role in mitochondrial membrane fusion, cristae structure, and bioenergetic function, OPA1 controls apoptosis by sequestering cytochrome c...

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Veröffentlicht in:Cell death and differentiation 2020-06, Vol.27 (6), p.1896-1906
Hauptverfasser: Anderson, Corey J., Kahl, Anja, Fruitman, Hannah, Qian, Liping, Zhou, Ping, Manfredi, Giovanni, Iadecola, Costantino
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Sprache:eng
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