Differential metabolism of inorganic arsenic in mice from genetically diverse Collaborative Cross strains

Mice have been frequently used to study the adverse effects of inorganic arsenic (iAs) exposure in laboratory settings. Like humans, mice metabolize iAs to monomethyl-As (MAs) and dimethyl-As (DMAs) metabolites. However, mice metabolize iAs more efficiently than humans, which may explain why some of...

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Veröffentlicht in:Archives of toxicology 2019-10, Vol.93 (10), p.2811-2822
Hauptverfasser: Stýblo, Miroslav, Douillet, Christelle, Bangma, Jacqueline, Eaves, Lauren A., de Villena, Fernando Pardo-Manuel, Fry, Rebecca
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Sprache:eng
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