A randomized, controlled, behavioral intervention to promote walking after abdominal organ transplantation: results from the LIFT study

Summary Kidney transplant recipients (KTRs) and liver transplant recipients (LTRs) have significant post‐transplant weight gain and low physical activity. We conducted a home‐based, remotely monitored intervention using wearable accelerometer devices to promote post‐transplant physical activity. We...

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Veröffentlicht in:Transplant international 2020-06, Vol.33 (6), p.632-643
Hauptverfasser: Serper, Marina, Barankay, Iwan, Chadha, Sakshum, Shults, Justine, Jones, Lauren S., Olthoff, Kim M., Reese, Peter P.
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Sprache:eng
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Zusammenfassung:Summary Kidney transplant recipients (KTRs) and liver transplant recipients (LTRs) have significant post‐transplant weight gain and low physical activity. We conducted a home‐based, remotely monitored intervention using wearable accelerometer devices to promote post‐transplant physical activity. We randomized 61 KTRs and 66 LTRs within 24 months of transplant to: (i) control, (ii) accelerometer or (iii) intervention: accelerometer paired with financial incentives and health engagement questions to increase steps by 15% from baseline every 2 weeks. The primary outcome was weight change. A co‐primary outcome for the two accelerometer arms was steps. Participants were recruited at a median of 9.5 [3–17] months post‐transplant. At 3 months, there were no significant differences in weight change across the three arms. The intervention arm was more likely to achieve ≥7000 steps compared to control with device (OR 1.99, 95% CI: 1.03–3.87); effect remained significant after adjusting for demographics, allograft, time from transplant and baseline weight. Adherence to target step goals was 74% in the intervention arm, 84% of health engagement questions were answered correctly. A pilot study with financial incentives and health engagement questions was feasible and led KTRs and LTRs to walk more, but did not affect weight. A definitive trial is warranted.
ISSN:0934-0874
1432-2277
DOI:10.1111/tri.13570